Evidence map›Paper›PMID 23828275›Full record

ReviewCalcified tissue international2013

Quality of life in sarcopenia and frailty.

René Rizzoli, Jean-Yves Reginster, Jean-François Arnal, Ivan Bautmans, Charlotte Beaudart, Heike Bischoff-Ferrari, Emmanuel Biver, Steven Boonen, Maria-Luisa Brandi, Arkadi Chines and 18 more

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Calcified tissue international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 189 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
189citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03955302 nacompletednot on this mapstarted 2018, after this paper: background citation

Ultrasound Assessment of Muscle Architecture Before and After the Implementation of a Physical Exercise Regime in the Water in a Frail Elderly Population

TypeinterventionalSponsorUniversity of ValenciaRan2018 to 2019Enrolled41ConditionsFrailty SyndromeArmsExercise
NCT06094413 nacompletednot on this mapstarted 2024, after this paper: background citation

The Effects of an 8-week Multicomponent Training Program on Quality of Life, Fear of Falling, &Amp; Physical Performance in Community-Dwelling Older Adults

TypeinterventionalSponsorGeisinger ClinicRan2024 to 2024Enrolled20ConditionsSarcopeniaArmsMulticomponent Training Intervention
3 · Its place in the literature

Who cites it

189 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Quality of life is substantially worse for community-dwelling older people living with frailty: systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
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  13. Effects of an 18-month community-based, multifaceted, exercise program on patient-reported outcomes in older adults at risk of fracture: secondary analysis of a randomised controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023
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129 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

René RizzoliService of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland. rene.rizzoli@unige.ch
Jean-Yves Reginster
Jean-François Arnal
Ivan Bautmans
Charlotte Beaudart
Heike Bischoff-Ferrari
Emmanuel Biver
Steven Boonen
Maria-Luisa Brandi
Arkadi Chines
Cyrus Cooper
Sol Epstein
Roger A Fielding
Bret Goodpaster
John A Kanis
Jean-Marc Kaufman
Andrea Laslop
Vincenzo Malafarina
Leocadio Rodriguez Mañas
Bruce H Mitlak
Richard O Oreffo
Jean Petermans
Kieran Reid
Yves Rolland
Avan Aihie Sayer
Yannis Tsouderos
Marjolein Visser
Olivier Bruyère

Funding

Medical Research Council G0400491Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_UP_A620_1014Medical Research Council MC_UP_A620_1015Medical Research Council MC_UU_12011/1Medical Research Council MC_UU_12011/2
6 · The paper itself

Abstract

The reduced muscle mass and impaired muscle performance that define sarcopenia in older individuals are associated with increased risk of physical limitation and a variety of chronic diseases. They may also contribute to clinical frailty. A gradual erosion of quality of life (QoL) has been evidenced in these individuals, although much of this research has been done using generic QoL instruments, particularly the SF-36, which may not be ideal in older populations with significant comorbidities. This review and report of an expert meeting presents the current definitions of these geriatric syndromes (sarcopenia and frailty). It then briefly summarizes QoL concepts and specificities in older populations and examines the relevant domains of QoL and what is known concerning QoL decline with these conditions. It calls for a clearer definition of the construct of disability, argues that a disease-specific QoL instrument for sarcopenia/frailty would be an asset for future research, and discusses whether there are available and validated components that could be used to this end and whether the psychometric properties of these instruments are sufficiently tested. It calls also for an approach using utility weighting to provide some cost estimates and suggests that a time trade-off study could be appropriate.

Indexed as

Frail ElderlyAgedAgingCachexiaComorbidityHumansObesityQuality of LifeSarcopeniaSurveys and Questionnaires

Identifiers

PMID23828275
PMCPMC3747610

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.