Evidence map›Paper›PMID 23827702›Full record

ArticleCell stem cell2013

Oncogenic miRNAs and the perils of losing control of a stem cell's epigenetic identity.

Piero Dalerba, Michael F Clarke

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell stem cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Piero DalerbaStanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA. pdalerba@stanford.edu
Michael F Clarke
Stanford Medicine · USStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathways that regulate epigenetic control of stem cell identity are critical to the molecular etiology of cancer. In back-to-back articles in Cell and Cell Stem Cell, Song et al. identify miR-22 as both a repressor of TET proteins and a powerful oncogene in the mammary epithelium and hematopoietic system.

Indexed as

Chromatin Assembly and DisassemblyEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticNeoplasm MetastasisAnimalsBreast NeoplasmsCell Transformation, NeoplasticDioxygenasesDNA-Binding ProteinsHematologic NeoplasmsHematopoietic Stem CellsHumansMicroRNAsMyelodysplastic SyndromesNeoplastic Stem CellsProto-Oncogene ProteinsDioxygenasesDNA-Binding ProteinsMicroRNAsMirn22 microRNA, mouseProto-Oncogene ProteinsTET2 protein, human

Identifiers

PMID23827702
OpenAlexW2090382046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.