ArticleInternational journal of ophthalmology2013
Effects of vernal and allergic conjunctivitis on severity of keratoconus.
Article in International journal of ophthalmology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 51 citations in OpenAlex.
- Corneal endothelial cells changes in different stages of Keratoconus: a multi-Centre clinical study.BMC ophthalmology · 2021Trial
- Inflammatory Mediators Involved in Conjunctival and Corneal Remodeling of Vernal Keratoconjunctivitis.Life (Basel, Switzerland) · 2026Review
- NEDD8 Promotes the Progression and Inflammation of Keratoconus by Increasing the Expression of YAP1.Investigative ophthalmology & visual science · 2026Article
- Using Artificial Intelligence for an Efficient Prediction of Outcomes of Deep Anterior Lamellar Keratoplasty (DALK) in Advanced Keratoconus.Translational vision science & technology · 2025Article
- Increased inflammatory mediators in the ocular surface tissue in keratoconus.Molecular vision · 2024Article
- Tear Fluid Inflammatory Proteome Analysis Highlights Similarities Between Keratoconus and Allergic Conjunctivitis.Investigative ophthalmology & visual science · 2023Article
- Systemic Associations with Keratoconus.Life (Basel, Switzerland) · 2023Review
- Cellular mechanisms and effects of IL-4 receptor blockade in experimental conjunctivitis evoked by skin inflammation.JCI insight · 2023Article
- Clinical Study on Corneal Topographical Changes in Vernal Keratoconjunctivitis by Using OCULUS Pentacam®.Cureus · 2023Article
- Management Outcomes in Pediatric Keratoconus: Childhood Keratoconus Study.Journal of ophthalmology · 2022Article
- Ovalbumin-Induced Allergic Inflammation Diminishes Cross-Linked Collagen Structures in an Experimental Rabbit Model of Corneal Cross-Linking.Frontiers in medicine · 2022Article
- Identification of Key Genes and Molecular Pathways in Keratoconus: Integrating Text Mining and Bioinformatics Analysis.BioMed research international · 2022Article
- Environmental Risk Factors Associated With the Need for Penetrating Keratoplasty in Patients With Keratoconus.Cureus · 2021Article
- Pathogenic alleles in microtubule, secretory granule and extracellular matrix-related genes in familial keratoconus.Human molecular genetics · 2021Article
- Changes in Anterior and Posterior Corneal Elevation in Patients With Allergic Conjunctivitis.Frontiers in medicine · 2021Article
- Increased lacrimal inflammatory mediators in patients with keratoconus.Molecular vision · 2021Article
- Relevance of IgE, allergy and eye rubbing in the pathogenesis and management of Keratoconus.Indian journal of ophthalmology · 2020Review
- Relationship between tear eotaxin-2 and MMP-9 with ocular allergy and corneal topography in keratoconus patients.International ophthalmology · 2020Article
- Optimal management of pediatric keratoconus: challenges and solutions.Clinical ophthalmology (Auckland, N.Z.) · 2019Article
- Corneal Morphologic Characteristics in Patients With Down Syndrome.JAMA ophthalmology · 2018Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo demonstrate the effects of two different types of allergic conjunctivitis on severity of keratoconus (KC).
methodsWe retrospectively reviewed the medical records of 171 KC patients referred between June 2010 and June 2011. The KC patients were divided into 3 groups as KC (group A), KC with vernal keratoconjunctivitis (VKC) (group B) and KC with allergic conjunctivitis (AC) (group C). Main outcome measures were demographic and ocular clinical features including age at presentation, gender, spherical equivalent (SE), best spectacle corrected visual acuity (BCVA), mean keratometric measurement (Km), central corneal thickness (CCT), and intraocular pressure (IOP). Groups were compared in term of study variables.
resultsThe median age at presentation was significantly lower in group B (P<0.001). According to the median SE (P=0.003), BCVA (P=0.022), Km (P<0.001), CCT (P=0.015) and Amsler-Krumeich classification (P<0.001), KC was more severe in group B. There was no significant difference in terms of IOP and corrected IOP among the groups (P=0.44), however there were 4 patients who had increased corrected IOP developed after topical corticosteroid use in group B. The differences among the groups persisted even after controlling for age and gender.
conclusionOur findings demonstrated a more severe KC in VKC patients despite their younger age which suggests evaluation of VKC patients as a separate group in keratoconus disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.