ArticleInternational journal of clinical and experimental pathology2013
HPV frequency in penile carcinoma of Mexican patients: important contribution of HPV16 European variant.
Article in International journal of clinical and experimental pathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- Prevalence of the most common types of high-risk HPV and p16Postepy dermatologii i alergologii · 2026Article
- Human Papillomavirus Infection in Penile Cancer: Multidimensional Mechanisms and Vaccine Strategies.International journal of molecular sciences · 2023Review
- Human papillomavirus genotypes and P16INK4A expression in squamous penile carcinoma in Mexican patients.BMC infectious diseases · 2019Article
- Human papillomavirus (HPV) genotype distribution in penile carcinoma: Association with clinic pathological factors.PloS one · 2018Article
- Lifestyle factors and oncogenic papillomavirus infection in a high-risk male population.PloS one · 2017Article
- HPV16 variants distribution in invasive cancers of the cervix, vulva, vagina, penis, and anus.Cancer medicine · 2016Article
- DAPK1, MGMT and RARB promoter methylation as biomarkers for high-grade cervical lesions.International journal of clinical and experimental pathology · 2015Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The role of human papillomavirus (HPV) infection in penile carcinoma (PeC) is currently reported and about half of the PeC is associated with HPV16 and 18. We used a PCR-based strategy by using HPV general primers to analyze 86 penile carcinomas paraffin-embedded tissues. Some clinical data, the histological subtype, growth pattern, and differentiation degree were also collected. The amplified fragments were then sequenced to confirm the HPV type and for HPV16/18 variants. DNA samples were also subjected to relative real time PCR for hTERC gene copy number. Some clinical data were also collected. Global HPV frequency was 77.9%. Relative contributions was for HPV16 (85%), 31 (4.4%), 11 (4.4%), 58, 33, 18, and 59 (1.4% each one). Sequence analysis of HPV16 identified European variants and Asian-American (AAb-c) variants in 92% and in 8% of the samples, respectively. Furthermore hTERC gene amplification was observed in only 17% of the cases. Our results suggest that some members of HPV A9 group (represented by HPV16, 58, and 31) are the most frequent among PeC patients studied with an important contribution from HPV16 European variant. The hTERC gene amplification could be poorly related to penile epithelial tissue.
Indexed as
Identifiers
23826423PMC3693207W1566324103What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.