SynthesisPloS one2013
Legume consumption and colorectal adenoma risk: a meta-analysis of observational studies.
Synthesis in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Legume intake and risk of prostate cancer: a meta-analysis of prospective cohort studies.Oncotarget · 2017Pooled it
- Identification and monitoring of metabolite markers of dry bean consumption in parallel human and mouse studies.Molecular nutrition & food research · 2015Trial
- Food Crops (Poaceae, Solanaceae, and Fabaceae) with Anti-Cancer Nutraceutical Prospects: A Review of Plant Extracts.Molecules (Basel, Switzerland) · 2026Review
- Association between legume consumption and risk of esophageal cancer among Chinese adults: a 17-year prospective cohort study.Cancer causes & control : CCC · 2025Article
- The Cardioprotective Properties of Pulses and the Molecular Mechanisms of Their Action.International journal of molecular sciences · 2025Review
- Common Bean Suppresses Hepatic Ceramide Metabolism in a Mouse Model of Metabolic Dysfunction-Associated Steatotic Liver Disease.Nutrients · 2024Article
- Legumes and pulses - a scoping review for Nordic Nutrition Recommendations 2023.Food & nutrition research · 2024Article
- Legumes: A Vehicle for Transition to Sustainability.Nutrients · 2023Review
- Article
- Plasma, urine, and stool metabolites in response to dietary rice bran and navy bean supplementation in adults at high-risk for colorectal cancer.Frontiers in gastroenterology (Lausanne, Switzerland) · 2023Article
- Phenolic content, antioxidant, cytotoxic and antiproliferative effects of fractions ofHeliyon · 2021Article
- Consumption Preferences of Pulses in the Diet of Polish People: Motives and Barriers to Replace Animal Protein with Vegetable Protein.Nutrients · 2021Article
- Influence of dietary isoflavone intake on gastrointestinal symptoms in ulcerative colitis individuals in remission.World journal of gastroenterology · 2017Article
- Dietary Green Pea Protects against DSS-Induced Colitis in Mice Challenged with High-Fat Diet.Nutrients · 2017Article
- Bowman-Birk inhibitors from legumes as colorectal chemopreventive agents.World journal of gastroenterology · 2014Review
- Perceived role of hot food in the pathogenesis of oesophageal cancer: a qualitative study in the Arsi Zone, Oromia, Central Ethiopia.Journal of nutritional scienceArticle
- Pea,Pharmacognosy reviewsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe anticancer effects of legumes have been explored extensively, but evidence from epidemiologic studies on colorectal adenoma is controversial. We performed a meta-analysis to assess these issues.
methodsA systemic search of several databases was conducted for relevant studies evaluating the relationship between legume intake and adenoma risk, with no language restriction, from January 1, 1966, to April 1, 2013.
resultsThree cohort and eleven case control studies with 8,380 cases and a total of 101,856 participants were included in the analysis; the pooled odds ratio (95% confidence interval) for the highest vs. lowest consumption categories was 0.83 (0.75-0.93), with moderate level of heterogeneity (I(2) = 25.9% and P = 0.146) based on a random effects model. A decreased risk of adenoma was also observed in most of our subgroup meta-analyses.
conclusionsHigher intake of legumes significantly reduced the risk of colorectal adenoma in our meta-analysis. Nevertheless, due to possible confounders and bias, further investigations are warranted to confirm this relationship.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.