ArticleIndian journal of anaesthesia2013
The role of melatonin in anaesthesia and critical care.
Article in Indian journal of anaesthesia, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of the Effects of Melatonin on Preoperative Anxiety and Postoperative Analgesia in Children Undergoing Surgery: a Prospective, Randomized Clinical Trial
Premedication With Melatonin vs. Placebo in Patients Undergoing Interventional Pain Procedure
Does Light and Noise Isolation Change the Melatonin Levels and Inflammatory Response After Cranial Surgery in an Intensive Care Unit
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Efficacy and Safety of Preoperative Melatonin for Women Undergoing Cesarean Section: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.Medicina (Kaunas, Lithuania) · 2023Pooled it
- The Effect of Preoperative Oral Melatonin on Postoperative Pain after Lumbar Disc Surgery: A Double-Blinded Randomized Clinical Trial.Ethiopian journal of health sciences · 2022Trial
- Comparison of the effects of preoperative melatonin or vitamin C administration on postoperative analgesia.Bosnian journal of basic medical sciences · 2020Trial
- A Comparison of the Effect of Two Doses of Oral Melatonin as Premedication on Orientation Score, Induction Compliance, and Emergency Agitation of Children Undergoing Elective Surgeries: A Double-Blinded Randomized Trial.Anesthesiology research and practice · 2025Article
- A Comprehensive Review on the Role of Melatonin's Anesthetic Applications in Pediatric Care.Cureus · 2024Review
- An In Silico Investigation of the Molecular Interactions between Volatile Anesthetics and Actin.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Targeting Mitochondrial and Brain Injury Markers in Acquired Brain Injuries: A Randomized, Double-Blind, Placebo-Controlled Study with Melatonin.Advanced pharmaceutical bulletin · 2022Article
- Serum melatonin concentration in critically ill patients randomized to sedation or non-sedation.Annals of intensive care · 2021Article
- Biomarkers Associated with the Outcome of Traumatic Brain Injury Patients.Brain sciences · 2017Review
- Melatonin - marvel in the making?Indian journal of anaesthesia · 2016Article
- A comparison of the effect of two doses of oral melatonin with oral midazolam and placebo on pre-operative anxiety, cognition and psychomotor function in children: A randomised double-blind study.Indian journal of anaesthesia · 2016Article
- Role of melatonin in attenuation of haemodynamic responses to laryngoscopy and intubation.Indian journal of anaesthesia · 2016Article
- Chronic fluorosis: The disease and its anaesthetic implications.Indian journal of anaesthesia · 2016Article
- Agomelatine and migraine management: a successfully treated case series.Therapeutic advances in psychopharmacology · 2015Article
- Experimental treatments for mitochondrial dysfunction in sepsis: A narrative review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Review
- The Efficacy of Oral Melatonin in Improving Sleep in Cancer Patients with Insomnia: A Randomized Double-Blind Placebo-Controlled Study.Indian journal of palliative careArticle
- Melatonin Supplementation May Improve the Outcome of Patients with Hemorrhagic Stroke in the Intensive Care Unit.Journal of research in pharmacy practiceArticle
- Effect of preoperative melatonin on anxiety and pain in patient undergoing phacoemulsification cataract surgery.Oman journal of ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melatonin is a neurohormone secreted by the pineal gland. It is widely present in both plant and animal sources. In several countries, it is sold over the counter as tablets and as food supplement or additive. Currently, it is most often used to prevent jet lag and to induce sleep. It has been and is being used in several clinical trials with different therapeutic approaches. It has sedative, analgesic, anti-inflammatory, anti-oxidative and chronobiotic effects. In the present review, the potential therapeutic benefits of melatonin in anaesthesia and critical care are presented. This article aims to review the physiological properties of melatonin and how these could prove useful for several clinical applications in perioperative management, critical care and pain medicine. The topic was handsearched from textbooks and journals and electronically from PubMed, and Google scholar using text words.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.