ArticlePloS one2013
Phytoplasma-Responsive microRNAs Modulate Hormonal, Nutritional, and Stress Signalling Pathways in Mexican Lime Trees.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Extended phenotype of phytoplasmas in eukaryotic systems: mechanisms and ecological implications.Frontiers in plant science · 2026Review
- Comprehensive genomic and functional characterization of a phytoplasma associated with root retardation, early bolting, witches'-broom, and phyllody in daikon (Frontiers in microbiology · 2025Article
- EnhancingFrontiers in plant science · 2024Article
- Article
- Differential Expression of miRNAs Involved in Response toPlants (Basel, Switzerland) · 2023Article
- New Cross-Talks between Pathways Involved in Grapevine Infection with 'Plants (Basel, Switzerland) · 2021Article
- Differential Response of Grapevine to Infection with 'International journal of molecular sciences · 2021Article
- MicroRNAs in Woody Plants.Frontiers in plant science · 2021Review
- Pre-symptomatic modified phytohormone profile is associated with lower phytoplasma titres in an Arabidopsis seor1ko line.Scientific reports · 2020Article
- Salinity-associated microRNAs and their potential roles in mediating salt tolerance in rice colonized by the endophytic root fungus Piriformospora indica.Functional & integrative genomics · 2019Article
- Plant Hormones in Phytoplasma Infected Plants.Frontiers in plant science · 2019Review
- ceRNA Cross-Talk in Paulownia Witches' Broom Disease.International journal of molecular sciences · 2018Article
- MiRNA-seq-based profiles of miRNAs in mulberry phloem sap provide insight into the pathogenic mechanisms of mulberry yellow dwarf disease.Scientific reports · 2018Article
- miRVIT: A Novel miRNA Database and Its Application to UncoverFrontiers in plant science · 2018Article
- Comparative Proteomic Analysis ofInternational journal of genomics · 2017Article
- Article
- Article
- Discovery of microRNAs and transcript targets related to witches' broom disease in Paulownia fortunei by high-throughput sequencing and degradome approach.Molecular genetics and genomics : MGG · 2016Article
- Genome-Wide Identification and Analysis of MicroRNAs Involved in Witches'-Broom Phytoplasma Response in Ziziphus jujuba.PloS one · 2016Article
- MicroRNA Signatures of Drought Signaling in Rice Root.PloS one · 2016Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWitches' broom disease of Mexican lime (Citrus aurantifolia L.), which is associated to the phytoplasma 'Candidatus Phytoplasma aurantifolia', is a devastating disease that results in significant economic losses. Plants adapt to biotic stresses by regulating gene expression at the transcriptional and post-transcriptional levels. MicroRNAs (miRNAs) are a recently identified family of molecules that regulate plant responses to environmental stresses through post-transcriptional gene silencing.
methodsUsing a high-throughput approach to sequence small RNAs, we compared the expression profiles of miRNAs in healthy Mexican lime trees and in plants infected with 'Ca. P. aurantifolia'.
resultsOur results demonstrated the involvement of different miRNAs in the response of Mexican lime trees to infection by 'Ca. P. aurantifolia'. We identified miRNA families that are expressed differentially upon infection with phytoplasmas. Most of the miRNAs had variants with small sequence variations (isomiRs), which are expressed differentially in response to pathogen infection.
conclusionsIt is likely that the miRNAs that are expressed differentially in healthy and phytoplasma-infected Mexican lime trees are involved in coordinating the regulation of hormonal, nutritional, and stress signalling pathways, and the complex interactions between them. Future research to elucidate the roles of these miRNAs should improve our understanding of the level of diversity of specific plant responses to phytoplasmas.
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