Trial reportEuropean journal of applied physiology2013
Effects of high vs. moderate exercise intensity during interval training on lipids and adiponectin levels in obese young females.
Trial report in European journal of applied physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02303470 (Vigorous Exercise Versus Moderate Exercise to Improve Glucose Metabolism and Metabolic Parameters in Women With Polycystic Ovary Syndrome and Insulin Resistance), which is not on this map. Cited by 160 papers, 22 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Vigorous Exercise Versus Moderate Exercise to Improve Glucose Metabolism and Metabolic Parameters in Women With Polycystic Ovary Syndrome and Insulin Resistance: A Prospective Randomized Pilot Study
Who cites it
160 citing papers in PubMed, 22 syntheses or guidelines pooled it, 329 citations in OpenAlex.
- Effects of high-intensity interval training on body composition, cardiorespiratory fitness, and selected lipid outcomes in adult women with overweight or obesity: a systematic review and meta-analysis.Frontiers in physiology · 2026Pooled it
- Pooled it
- Exercise training modalities for cardiorespiratory fitness and blood pressure in children and adolescents with obesity: a systematic review and network meta-analysis.Frontiers in public health · 2026Pooled it
- Effects of high-intensity interval training on cardiorespiratory fitness in adolescents with overweight or obesity: a systematic review and dose-response meta-analysis.Frontiers in physiology · 2026Pooled it
- Effects of exercise on cardiorespiratory fitness in children and adolescents with overweight and obesity: a systematic review and meta-analysis of 72 randomized controlled trials.BMC public health · 2025Pooled it
- Pooled it
- The effect of sprint interval training on key cardiometabolic risk factors in children and adolescents: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- The Effects of High-Intensity Interval Training on Cardiometabolic Health in Children and Adolescents: A Systematic Review and Meta-Analysis.Journal of sports science & medicine · 2024Pooled it
- Process evaluation of school-based high-intensity interval training interventions for children and adolescents: a systematic review and meta-analysis of randomized controlled trials.BMC public health · 2024Pooled it
- Effect of high-intensity interval training on cardiorespiratory in children and adolescents with overweight or obesity: a meta-analysis of randomized controlled trials.Frontiers in public health · 2024Pooled it
- Physical activity interventions for cardiopulmonary fitness in obese children and adolescents: a systematic review and meta-analysis.BMC pediatrics · 2023Pooled it
- The effects of exercise training on insulin resistance in children and adolescents with overweight or obesity: a systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Comparative effectiveness of school-based exercise interventions on physical fitness in children and adolescents: a systematic review and network meta-analysis.Frontiers in public health · 2023Pooled it
- Pooled it
- School-based high-intensity interval training programs in children and adolescents: A systematic review and meta-analysis.PloS one · 2022Pooled it
- A Meta-Analysis of High-Intensity Interval Training on Glycolipid Metabolism in Children With Metabolic Disorders.Frontiers in pediatrics · 2022Pooled it
- Pooled it
- High Intensity Interval Training (HIIT) Improves Cardiorespiratory Fitness (CRF) in Healthy, Overweight and Obese Adolescents: A Systematic Review and Meta-Analysis of Controlled Studies.International journal of environmental research and public health · 2020Pooled it
- Pooled it
- What change in body mass index is associated with improvement in percentage body fat in childhood obesity? A meta-regression.BMJ open · 2019Pooled it
100 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe investigate the effects of 12-week interval training of moderate- or high-intensity exercise on blood lipids and plasma levels of adiponectin.
methodsThirty-four obese adolescent females [age = 15.9 ± 0.3 years; BMI and BMI-Z-score = 30.8 ± 1.6 kg/m(2) and 3 ± 0.3, respectively], were randomized to high-intensity interval training (HIIT, n = 11), moderate-intensity interval training (MIIT, n = 11), or a control group (CG, n = 12). Maximal oxygen uptake ([Formula: see text]), maximal aerobic speed (MAS), plasma lipids and adiponectin levels were measured in all subjects before and after training.
resultsFollowing the training program, in both training groups, body mass, BMI-Z-score, and percentage body fat (% BF) decreased, while [Formula: see text] and MAS increased. Low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and adiponectin levels were positively altered (-12.6 and -7.4 %; 6.3 and 8.0 %; 35.8 and 16.2 %; high to moderate training program, respectively). Waist circumference, triglyceride and total cholesterol decreased only in HIIT group (-3.5; -5.3 and -7.0 %, respectively, in all P < 0.05). Significant decrease in the usual index of insulin resistance (HOMA-IR) occurred in HIIT and MIIT groups (-29.2 ± 5.3 and -18.4 ± 8.6 %, respectively; P < 0.01).
conclusionThe results show that HIIT positively changes blood lipids and adiponectin variables in obese adolescent girls, resulting in improved insulin sensitivity, as attested by a lower HOMA-IR, and achieving better results compared to moderate-intensity exercise.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.