ArticlePloS one2013
A Large Plasmodium vivax Reservoir and Little Population Structure in the South Pacific.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 72 citations in OpenAlex.
- UnderstandingiScience · 2026Article
- Parasite genotypes and host immune mediators in primary and recurrent episodes of vivax Malaria in Colombia.Revista peruana de medicina experimental y salud publica · 2025Article
- Population genetics ofFrontiers in genetics · 2025Article
- Tracing the origins of Plasmodium vivax resurgence after malaria elimination on Aneityum Island in Vanuatu.Communications medicine · 2024Article
- Heterogeneity in prevalence of subclinical Plasmodium falciparum and Plasmodium vivax infections but no parasite genomic clustering in the Chittagong Hill Tracts, Bangladesh.Malaria journal · 2022Article
- Prevalence and force of Plasmodium vivax blood-stage infection and associated clinical malaria burden in the Brazilian Amazon.Memorias do Instituto Oswaldo Cruz · 2022Article
- Malaria in the 'Omics Era'.Genes · 2021Review
- The changing epidemiology of Plasmodium vivax: Insights from conventional and novel surveillance tools.PLoS medicine · 2021Review
- Monitoring Plasmodium falciparum and Plasmodium vivax using microsatellite markers indicates limited changes in population structure after substantial transmission decline in Papua New Guinea.Molecular ecology · 2020Article
- Spatial and genetic clustering of Plasmodium falciparum and Plasmodium vivax infections in a low-transmission area of Ethiopia.Scientific reports · 2020Article
- SNP barcodes provide higher resolution than microsatellite markers to measure Plasmodium vivax population genetics.Malaria journal · 2020Article
- Whole genome sequencing of Plasmodium vivax isolates reveals frequent sequence and structural polymorphisms in erythrocyte binding genes.PLoS neglected tropical diseases · 2020Article
- Confirmation of the absence of local transmission and geographic assignment of imported falciparum malaria cases to China using microsatellite panel.Malaria journal · 2020Article
- Dynamics of Plasmodium vivax populations in border areas of the Greater Mekong sub-region during malaria elimination.Malaria journal · 2020Article
- Malaria Molecular Epidemiology: An Evolutionary Genetics Perspective.Microbiology spectrum · 2019Review
- Increasingly inbred and fragmented populations of Plasmodium vivax associated with the eastward decline in malaria transmission across the Southwest Pacific.PLoS neglected tropical diseases · 2018Article
- Frequent Spread of Plasmodium vivax Malaria Maintains High Genetic Diversity at the Myanmar-China Border, Without Distance and Landscape Barriers.The Journal of infectious diseases · 2017Article
- Substantial population structure of Plasmodium vivax in Thailand facilitates identification of the sources of residual transmission.PLoS neglected tropical diseases · 2017Article
- Population Genetics of Plasmodium vivax in Four High Malaria Endemic Areas in Thailand.The Korean journal of parasitology · 2017Article
- Plasmodium vivax genetic diversity and heterozygosity in blood samples and resulting oocysts at the Thai-Myanmar border.Malaria journal · 2017Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe importance of Plasmodium vivax in malaria elimination is increasingly being recognized, yet little is known about its population size and population genetic structure in the South Pacific, an area that is the focus of intensified malaria control.
methodsWe have genotyped 13 microsatellite markers in 295 P. vivax isolates from four geographically distinct sites in Papua New Guinea (PNG) and one site from Solomon Islands, representing different transmission intensities.
resultsDiversity was very high with expected heterozygosity values ranging from 0.62 to 0.98 for the different markers. Effective population size was high (12'872 to 19'533 per site). In PNG population structuring was limited with moderate levels of genetic differentiation. F ST values (adjusted for high diversity of markers) were 0.14-0.15. Slightly higher levels were observed between PNG populations and Solomon Islands (F ST = 0.16).
conclusionsLow levels of population structure despite geographical barriers to transmission are in sharp contrast to results from regions of low P. vivax endemicity. Prior to intensification of malaria control programs in the study area, parasite diversity and effective population size remained high.
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