ArticleBMC plant biology2013
Different evolutionary histories of two cation/proton exchanger gene families in plants.
Article in BMC plant biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Increased salt tolerance with overexpression of cation/proton antiporter 1 genes: a meta-analysis.Plant biotechnology journal · 2017Pooled it
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- Genomic survey and evolution analysis of calcium-dependent protein kinases in plants and their stress-responsive patterns in populus.BMC genomics · 2024Article
- Genome-wide characterization of the CPA gene family in potato and a preliminary functional analysis of its role in NaCl tolerance.BMC genomics · 2024Article
- Genetic Determinants of Fiber-Associated Traits in Flax Identified by Omics Data Integration.International journal of molecular sciences · 2022Article
- Evolutionary Significance of NHX Family and NHX1 in Salinity Stress Adaptation in the GenusInternational journal of molecular sciences · 2022Article
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- HKT sodium and potassium transporters in Arabidopsis thaliana and related halophyte species.Physiologia plantarum · 2021Review
- Genome-Wide Identification and Functional Characterization of the Cation Proton Antiporter (CPA) Family Related to Salt Stress Response in Radish (International journal of molecular sciences · 2020Article
- New Insights into the Structure-Function Relationship of the Endosomal-Type NaInternational journal of molecular sciences · 2020Article
- Phylogenetic Diversity and Physiological Roles of Plant Monovalent Cation/HFrontiers in plant science · 2020Review
- Molecular Evidence for Functional Divergence and Decay of a Transcription Factor Derived from Whole-Genome Duplication in Arabidopsis thaliana.Plant physiology · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGene duplication events have been proposed to be involved in the adaptation of plants to stress conditions; precisely how is unclear. To address this question, we studied the evolution of two families of antiporters. Cation/proton exchangers are important for normal cell function and in plants, Na+,K+/H+ antiporters have also been implicated in salt tolerance. Two well-known plant cation/proton antiporters are NHX1 and SOS1, which perform Na+ and K+ compartmentalization into the vacuole and Na+ efflux from the cell, respectively. However, our knowledge about the evolution of NHX and SOS1 stress responsive gene families is still limited.
resultsIn this study we performed a comprehensive molecular evolutionary analysis of the NHX and SOS1 families. Using available sequences from a total of 33 plant species, we estimated gene family phylogenies and gene duplication histories, as well as examined heterogeneous selection pressure on amino acid sites. Our results show that, while the NHX family expanded and specialized, the SOS1 family remained a low copy gene family that appears to have undergone neofunctionalization during its evolutionary history. Additionally, we found that both families are under purifying selection although SOS1 is less constrained.
conclusionsWe propose that the different evolution histories are related with the proteins' function and localization, and that the NHX and SOS1 families are examples of two different evolutionary paths through which duplication events may result in adaptive evolution of stress tolerance.
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