Evidence map›Paper›PMID 23821595›Full record

ArticleGenetics2013

Cloning and characterization of a critical regulator for preharvest sprouting in wheat.

Shubing Liu, Sunish K Sehgal, Jiarui Li, Meng Lin, Harold N Trick, Jianming Yu, Bikram S Gill, Guihua Bai

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
18.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 177 citations in OpenAlex.

  1. Article
  2. Identification of a novel major QTL and F-box candidate genes controlling seed dormancy in common wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Unlocking the genetic potential ofFrontiers in plant science · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Breeding Wheat (Plants (Basel, Switzerland) · 2025
    Review
  14. Genetic loci and novel candidate causal genes for preharvest sprouting resistance in wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  15. Article
  16. Progress and innovations of gene cloning in wheat and its close relatives.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Shubing LiuDepartment of Agronomy, Kansas State University, Manhattan, Kansas 66506.
Sunish K Sehgal
Jiarui Li
Meng Lin
Harold N Trick
Jianming Yu
Bikram S Gill
Guihua Bai
Kansas State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sprouting of grains in mature spikes before harvest is a major problem in wheat (Triticum aestivum) production worldwide. We cloned and characterized a gene underlying a wheat quantitative trait locus (QTL) on the short arm of chromosome 3A for preharvest sprouting (PHS) resistance in white wheat using comparative mapping and map-based cloning. This gene, designated TaPHS1, is a wheat homolog of a MOTHER OF FLOWERING TIME (TaMFT)-like gene. RNA interference-mediated knockdown of the gene confirmed that TaPHS1 positively regulates PHS resistance. We discovered two causal mutations in TaPHS1 that jointly altered PHS resistance in wheat. One GT-to-AT mutation generates a mis-splicing site, and the other A-to-T mutation creates a premature stop codon that results in a truncated nonfunctional transcript. Association analysis of a set of wheat cultivars validated the role of the two mutations on PHS resistance. The molecular characterization of TaPHS1 is significant for expediting breeding for PHS resistance to protect grain yield and quality in wheat production.

Indexed as

Amino Acid SequenceChromosomes, PlantCloning, MolecularCodon, TerminatorMolecular Sequence DataMutationPlant DevelopmentPlant ProteinsQuantitative Trait LociTriticumCodon, TerminatorPlant ProteinsDNA markergene clonePreharvesting sproutingRNA interferencewheat abiotic stress

Identifiers

PMID23821595
PMCPMC3761307
OpenAlexW2128439382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.