ArticleEnvironmental health perspectives2013
Improved air quality and attenuated lung function decline: modification by obesity in the SAPALDIA cohort.
Article in Environmental health perspectives, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis.The European respiratory journal · 2015Pooled it
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- Associations of improved air quality with lung function growth from childhood to adulthood: the BAMSE study.The European respiratory journal · 2023Article
- Asthma interactions between obesity and other risk factors.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022Review
- Air Pollutants and Asthma Hospitalization in the Medicaid Population.American journal of respiratory and critical care medicine · 2022Article
- Swiss Cohort & Biobank - The White Paper.Public health reviews · 2022Article
- Causal Effects of Body Mass Index on Airflow Obstruction and Forced Mid-Expiratory Flow: A Mendelian Randomization Study Taking Interactions and Age-Specific Instruments Into Consideration Toward a Life Course Perspective.Frontiers in public health · 2021Article
- Air pollution inhalation during acute exercise is dependent of the body mass index and ventilation of young men.Environmental science and pollution research international · 2020Article
- Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study.Thorax · 2020Article
- The mediating effect of immune markers on the association between ambient air pollution and adult-onset asthma.Scientific reports · 2019Article
- Can the effects of outdoor air pollution on asthma be mitigated?The Journal of allergy and clinical immunology · 2019Article
- The Role of Socioeconomic Status in the Association of Lung Function and Air Pollution-A Pooled Analysis of Three Adult ESCAPE Cohorts.International journal of environmental research and public health · 2019Article
- European Respiratory Society International Congress 2018: four shades of epidemiology and tobacco control.ERJ open research · 2019Review
- Environmental exposures and systemic hypertension are risk factors for decline in lung function.Thorax · 2018Article
- Longitudinal study of lung function in pregnant women: Influence of parity and smoking.Clinics (Sao Paulo, Brazil) · 2017Article
- Abdominal adiposity intensifies the negative effects of ambient air pollution on lung function in Korean men.International journal of obesity (2005) · 2017Article
- Ozone Exposure, Cardiopulmonary Health, and Obesity: A Substantive Review.Chemical research in toxicology · 2017Review
- Time to harmonize national ambient air quality standards.International journal of public health · 2017Article
- A joint ERS/ATS policy statement: what constitutes an adverse health effect of air pollution? An analytical framework.The European respiratory journal · 2017Article
- Susceptibility Factors Relevant for the Association Between Long-Term Air Pollution Exposure and Incident Asthma.Current environmental health reports · 2016Review
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Authors and funding
14 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAir pollution and obesity are hypothesized to contribute to accelerated decline in lung function with age through their inflammatory properties.
objectiveWe investigated whether the previously reported association between improved air quality and lung health in the population-based SAPALDIA cohort is modified by obesity.
methodsWe used adjusted mixed-model analyses to estimate the association of average body mass index (BMI) and changes in particulate matter with aerodynamic diameter ≤ 10 µm (PM10; ΔPM10) with lung function decline over a 10-year follow-up period.
resultsLung function data and complete information were available for 4,664 participants. Age-related declines in lung function among participants with high average BMI were more rapid for FVC (forced vital capacity), but slower for FEV1/FVC (forced expiratory volume in 1 sec/FVC) and FEF25-75 (forced expiratory flow at 25-75%) than declines among those with low or normal average BMI. Improved air quality was associated with attenuated reductions in FEV1/FVC, FEF25-75, and FEF25-75/FVC over time among low- and normal-BMI participants, but not overweight or obese participants. The attenuation was most pronounced for ΔFEF25-75/FVC (30% and 22% attenuation in association with a 10-μg/m3 decrease in PM10 among low- and normal-weight participants, respectively.)
conclusionOur results point to the importance of considering health effects of air pollution exposure and obesity in parallel. Further research must address the mechanisms underlying the observed interaction.
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