ArticleParasitology research2013
Alteration in Bacillus thuringiensis toxicity by curing gut flora: novel approach for mosquito resistance management.
Article in Parasitology research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 52 citations in OpenAlex.
- Selected gut bacteria promote mosquito larval growth through the regulation of ionic microenvironment and protease expression.iScience · 2025Article
- Gut bacteria contribute to fenvalerate resistance in the tomato leafminer, Tuta absoluta.Scientific reports · 2025Article
- Carry-over effects of Bacillus thuringiensis on tolerant Aedes albopictus mosquitoes.Parasites & vectors · 2024Article
- Mosquito Gut Microbiota: A Review.Pathogens (Basel, Switzerland) · 2024Review
- Cry1Ac Mixed with Gentamicin Influences the Intestinal Microbial Diversity and Community Composition of Pink Bollworms.Life (Basel, Switzerland) · 2023Article
- Host resistance to Bacillus thuringiensis is linked to altered bacterial community within a specialist insect herbivore.Molecular ecology · 2021Article
- Article
- Microbiota and transcriptome changes of Culex pipiens pallens larvae exposed to Bacillus thuringiensis israelensis.Scientific reports · 2021Article
- Which Is Stronger? A Continuing Battle Between Cry Toxins and Insects.Frontiers in microbiology · 2021Review
- The Tripartite Interaction of Host Immunity-Toxins · 2020Review
- The Challenges of Microbial Control of Mosquito-Borne Diseases Due to the Gut Microbiome.Frontiers in genetics · 2020Review
- Microbiota potentialized larvicidal action of imidazolium salts against Aedes aegypti (Diptera: Culicidae).Scientific reports · 2019Article
- Survey of bacteria associated with western corn rootworm life stages reveals no difference between insects reared in different soils.Scientific reports · 2019Article
- Microbiota variations inPeerJ · 2019Article
- Effect of environmental variables and kdr resistance genotype on survival probability and infection rates in Anopheles gambiae (s.s.).Parasites & vectors · 2018Article
- Review
- Bacterial microbiota of Aedes aegypti mosquito larvae is altered by intoxication with Bacillus thuringiensis israelensis.Parasites & vectors · 2018Article
- Temporal Variations of Microbiota Associated with the Immature Stages of Two Florida Culex Mosquito Vectors.Microbial ecology · 2017Article
- Gut symbiont enhances insecticide resistance in a significant pest, the oriental fruit fly Bactrocera dorsalis (Hendel).Microbiome · 2017Article
- Immuno-physiological adaptations confer wax moth Galleria mellonella resistance to Bacillus thuringiensis.Virulence · 2016Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mosquitoes are known for acquiring resistance against insecticides in many ways, namely target side mutation, enzyme modification, sequestration, quick elimination, etc. But, the role of microflora present in abundance in the larval midgut is less explored with respect to their role in insecticide resistance. During the course of their development, mosquitoes are continuously exposed to microbes and have naturally acquired midgut microbial flora. This midgut flora can modulate the mosquito's susceptibility to Bacillus thuringiensis (Bt) infection by degrading toxic Bt protein forms through an unknown mechanism. In this study, we show that microbe-free aseptic mosquito larvae displayed an increased susceptibility to Bt toxicity compared to larvae harboring natural microbial flora. Fourth instar larvae of Anopheles stephensi were treated separately with penicillin, streptomycin, erythromycin (100 μg/ml), and mixtures of all three antibiotics and then analyzed for Bt toxicity. We have also examined the influence of the mosquito's midgut microbial flora under microaerophilic condition on the Bt protein degradation through plate, broth, TLC, and UV-vis spectrophotometric assay. A better understanding of the roles of microbiota in preventing Bt toxicity to mosquitoes could potentially lead to the development of new sustainable mosquito control strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.