ReviewExperimental cell research2013
Techniques for assessing 3-D cell-matrix mechanical interactions in vitro and in vivo.
Review in Experimental cell research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- The Mechano-Immune-Vascular Activation Loop: An Integrative Conceptual Framework for Positive Feedback in Hypertension.International journal of molecular sciences · 2026Review
- Engineering Biomimetic 3D Microenvironments for Extracellular Vesicle Programming Toward Clinical Translation.International journal of molecular sciences · 2026Review
- Mobilization of subcutaneous fascia contributes to the vascularization and function of acellular adipose matrix via formation of vascular matrix complex.Materials today. Bio · 2025Article
- The effects of mechanical force on fibroblast behavior in cutaneous injury.Frontiers in surgery · 2023Review
- Spatially-resolved nanometer-scale measurement of cartilage extracellular matrix mobility.Osteoarthritis and cartilage · 2021Article
- ECM Stiffness Controls the Activation and Contractility of Corneal Keratocytes in Response to TGF-β1.Biophysical journal · 2020Article
- Fabrication of tough, anisotropic, chemical-crosslinker-free poly(vinyl alcohol) nanofibrous cryogelsRSC advances · 2020Article
- Three-dimensional culture and clinical drug responses of a highly metastatic human ovarian cancer HO-8910PM cells in nanofibrous microenvironments of three hydrogel biomaterials.Journal of nanobiotechnology · 2020Article
- Patch repair of deep wounds by mobilized fascia.Nature · 2019Article
- Assessment of Corneal Stromal Remodeling and Regeneration after Photorefractive Keratectomy.Scientific reports · 2018Article
- Native collagen hydrogel nanofibres with anisotropic structure using core-shell electrospinning.Scientific reports · 2018Article
- CCR4 is a determinant of melanoma brain metastasis.Oncotarget · 2017Article
- Role of corneal collagen fibrils in corneal disorders and related pathological conditions.International journal of ophthalmology · 2017Review
- Analysis of multiple types of human cells subsequent to bioprinting with electrospraying technology.Biomedical reports · 2016Article
- Integrating Concepts of Material Mechanics, Ligand Chemistry, Dimensionality and Degradation to Control Differentiation of Mesenchymal Stem Cells.Current opinion in solid state & materials science · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Cellular interactions with extracellular matrices (ECM) through the application of mechanical forces mediate numerous biological processes including developmental morphogenesis, wound healing and cancer metastasis. They also play a key role in the cellular repopulation and/or remodeling of engineered tissues and organs. While 2-D studies can provide important insights into many aspects of cellular mechanobiology, cells reside within 3-D ECMs in vivo, and matrix structure and dimensionality have been shown to impact cell morphology, protein organization and mechanical behavior. Global measurements of cell-induced compaction of 3-D collagen matrices can provide important insights into the regulation of overall cell contractility by various cytokines and signaling pathways. However, to understand how the mechanics of cell spreading, migration, contraction and matrix remodeling are regulated at the molecular level, these processes must also be studied in individual cells. Here we review the evolution and application of techniques for imaging and assessing local cell-matrix mechanical interactions in 3-D culture models, tissue explants and living animals.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.