SynthesisBMC pulmonary medicine2013
The health economic impact of disease management programs for COPD: a systematic literature review and meta-analysis.
Synthesis in BMC pulmonary medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cost and effects of integrated care: a systematic literature review and meta-analysis.The European journal of health economics : HEPAC : health economics in prevention and care · 2020Pooled it
- Trial
- Exploring the variation in implementation of a COPD disease management programme and its impact on health outcomes: a post hoc analysis of the RECODE cluster randomised trial.NPJ primary care respiratory medicine · 2015Trial
- Effectiveness of community-based integrated care in frail COPD patients: a randomised controlled trial.NPJ primary care respiratory medicine · 2015Trial
- Effectiveness of integrated disease management for primary care chronic obstructive pulmonary disease patients: results of cluster randomised trial.BMJ (Clinical research ed.) · 2014Trial
- Improving inhaler adherence in patients with chronic obstructive pulmonary disease: a cost-effectiveness analysis.Respiratory research · 2014Trial
- Impact of digital integrated health platforms on diabetes management: evidence from Tianjin, China.BMC health services research · 2025Article
- Influence of probable respiratory sarcopenia on chronic lung diseases: a population-based cohort study of community-dwelling Chinese older adults.Frontiers in medicine · 2025Article
- Feasibility, effectiveness and safety of self-management in pulmonary rehabilitation: a study protocol using a hybrid type 1 effectiveness-implementation design.Frontiers in rehabilitation sciences · 2023Article
- Using Telemedicine to Monitor the Patient with Chronic Respiratory Failure.Life (Basel, Switzerland) · 2021Review
- Article
- Review
- Methodological Quality of Economic Evaluations in Integrated Care: Evidence from a Systematic Review.International journal of integrated care · 2019Article
- Impact of a Health Management Program on Healthcare Outcomes among Patients on Augmentation Therapy for Alpha 1-Antitrypsin Deficiency: An Insurance Claims Analysis.Advances in therapy · 2018Article
- [Is the introduction of clinical management programs for patients with chronic obstructive pulmonary disease useful? Comparison of the effectiveness of two interventions on the clinical progress and care received].Atencion primaria · 2018Article
- Evaluation of the COPDnet integrated care model in patients with COPD: the study protocol.International journal of chronic obstructive pulmonary disease · 2018Article
- How to Improve Integrated Care for People with Chronic Conditions: Key Findings from EU FP-7 Project INTEGRATE and Beyond.International journal of integrated care · 2017Article
- Tele-medicine in respiratory diseases.Multidisciplinary respiratory medicine · 2017Review
- The contribution of symptoms and comorbidities to the economic impact of COPD: an analysis of the German COSYCONET cohort.International journal of chronic obstructive pulmonary disease · 2017Observational
- Telemedicine in chronic obstructive pulmonary disease.Breathe (Sheffield, England) · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is insufficient evidence of the cost-effectiveness of Chronic Obstructive Pulmonary Disease (COPD) Disease Management (COPD-DM) programs. The aim of this review is to evaluate the economic impact of COPD-DM programs and investigate the relation between the impact on healthcare costs and health outcomes. We also investigated the impact of patient-, intervention, and study-characteristics.
methodsWe conducted a systematic literature review to identify cost-effectiveness studies of COPD-DM. Where feasible, results were pooled using random-effects meta-analysis and explorative subgroup analyses were performed.
resultsSixteen papers describing 11 studies were included (7 randomized control trials (RCT), 2 pre-post, 2 case-control). Meta-analysis showed that COPD-DM led to hospitalization savings of €1060 (95% CI: €2040 to €80) per patient per year and savings in total healthcare utilization of €898 (95% CI: €1566 to €231) (excl. operating costs). In these health economic studies small but positive results on health outcomes were found, such as the St Georges Respiratory Questionnaire (SGRQ) score, which decreased with 1.7 points (95% CI: 0.5-2.9). There was great variability in DM interventions-, study- and patient-characteristics. There were indications that DM showed greater savings in studies with: severe COPD patients, patients with a history of exacerbations, RCT study design, high methodological quality, few different professions involved in the program, and study setting outside Europe.
conclusionsCOPD-DM programs were found to have favourable effects on both health outcomes and costs, but there is considerable heterogeneity depending on patient-, intervention-, and study-characteristics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.