Evidence map›Paper›PMID 23819124›Full record

ArticleBioMed research international2013

Mouse prostate epithelial luminal cells lineage originate in the basal layer where the primitive stem/early progenitor cells reside: implications for identifying prostate cancer stem cells.

Jianjun Zhou, Lionel Feigenbaum, Carole Yee, Hongbin Song, Clayton Yates

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Chemoresistance is mediated by ovarian cancer leader cells in vitro.Journal of experimental & clinical cancer research : CR · 2021
    Article
  2. Cancer stem cells in prostate cancer.Translational andrology and urology · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jianjun ZhouDepartment of Biology and Center for Cancer Research, Tuskegee University, Tuskegee, AL 36088, USA.
Lionel Feigenbaum
Carole Yee
Hongbin Song
Clayton Yates

Funding

Research Education CoreU54CA118623 · NCI · TUSKEGEE UNIVERSITY · PI STEPHEN O SODEKE · 2005 to 2026
$20.2M
THYMIC NURSE CELL ENVIRONMENT IN PATHOGENESIS OF SYSTEMIC LUPUS ERYTHEMATOSUSG12RR003059 · NCRR · TUSKEGEE UNIVERSITY · PI ROCHON, GILBERT L. · 1988 to 2011
$13.5M
INFRASTRUCTURE IIG12MD007585 · NIMHD · TUSKEGEE UNIVERSITY · PI YATES, CLAYTON · 2012 to 2016
$4.6M
NCI NIH HHS U54 CA118623NCRR NIH HHS G12 RR003059NCRR NIH HHS G12 RR03059-21A1NIMHD NIH HHS G12 MD007585
6 · The paper itself

Abstract

Prostate stem cells are thought to be responsible for generation of all prostate epithelial cells and for tissue maintenance. The lineage relationship between basal and luminal cells in the prostate is not well clarified. We developed a mouse model to trace cell fate and a mouse model with a slowly cycling cell label to provide insight into this question. The results obtained indicate that putative mouse prostate stem cells are likely to reside in the basal layer.

Indexed as

Cell LineageAnimalsCell CycleEpithelial CellsGenotyping TechniquesGreen Fluorescent ProteinsHumansIntegrasesKeratin-14Keratin-5MaleMiceMice, TransgenicNeoplastic Stem CellsProstateProstatic NeoplasmsCre recombinaseGreen Fluorescent ProteinsIntegrasesKeratin-14Keratin-5

Identifiers

PMID23819124
PMCPMC3683430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.