ArticlePLoS genetics2013
Extensive intra-kingdom horizontal gene transfer converging on a fungal fructose transporter gene.
Article in PLoS genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Horizontal gene transfer in Saccharomyces cerevisiae and other Saccharomycotina yeasts: a review.World journal of microbiology & biotechnology · 2026Review
- Characterization of three glycerol transporters with broad sugar specificities from Aspergillus niger.Applied microbiology and biotechnology · 2026Article
- Biotechnological applications of D-xylose-fermenting autochthonous yeasts in lignocellulosic biorefineries.Biotechnology for biofuels and bioproducts · 2026Review
- Distinctive domestication of farmhouse beer yeasts preserved pre-industrial genetic and phenotypic diversity.Current biology : CB · 2026Article
- Review
- Evolution and functional diversification of yeast sugar transporters.Essays in biochemistry · 2023Article
- A novel aminotransferase gene and its regulator acquired in Saccharomyces by a horizontal gene transfer event.BMC biology · 2023Article
- Article
- Electrophysiological characterization of a diverse group of sugar transporters from Trichoderma reesei.Scientific reports · 2021Article
- Categorization of Orthologous Gene Clusters in 92 Ascomycota Genomes Reveals Functions Important for Phytopathogenicity.Journal of fungi (Basel, Switzerland) · 2021Article
- Datamining and functional environmental genomics reassess the phylogenetics and functional diversity of fungal monosaccharide transporters.Applied microbiology and biotechnology · 2021Article
- Environment-dependent fitness gains can be driven by horizontal gene transfer of transporter-encoding genes.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Ancestral Function and Diversification of a Horizontally Acquired Oomycete Carboxylic Acid Transporter.Molecular biology and evolution · 2018Article
- Evidence for loss and reacquisition of alcoholic fermentation in a fructophilic yeast lineage.eLife · 2018Article
- Fungal Sex: The Basidiomycota.Microbiology spectrum · 2017Review
- Horizontal acquisition of toxic alkaloid synthesis in a clade of plant associated fungi.Fungal genetics and biology : FG & B · 2016Article
- Genomics and the making of yeast biodiversity.Current opinion in genetics & development · 2015Review
- A Novel Type Pathway-Specific Regulator and Dynamic Genome Environments of a Solanapyrone Biosynthesis Gene Cluster in the Fungus Ascochyta rabiei.Eukaryotic cell · 2015Article
- HGT-Finder: A New Tool for Horizontal Gene Transfer Finding and Application to Aspergillus genomes.Toxins · 2015Article
- Adaptive Horizontal Gene Transfers between Multiple Cheese-Associated Fungi.Current biology : CB · 2015Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Comparative genomics revealed in the last decade a scenario of rampant horizontal gene transfer (HGT) among prokaryotes, but for fungi a clearly dominant pattern of vertical inheritance still stands, punctuated however by an increasing number of exceptions. In the present work, we studied the phylogenetic distribution and pattern of inheritance of a fungal gene encoding a fructose transporter (FSY1) with unique substrate selectivity. 109 FSY1 homologues were identified in two sub-phyla of the Ascomycota, in a survey that included 241 available fungal genomes. At least 10 independent inter-species instances of horizontal gene transfer (HGT) involving FSY1 were identified, supported by strong phylogenetic evidence and synteny analyses. The acquisition of FSY1 through HGT was sometimes suggestive of xenolog gene displacement, but several cases of pseudoparalogy were also uncovered. Moreover, evidence was found for successive HGT events, possibly including those responsible for transmission of the gene among yeast lineages. These occurrences do not seem to be driven by functional diversification of the Fsy1 proteins because Fsy1 homologues from widely distant lineages, including at least one acquired by HGT, appear to have similar biochemical properties. In summary, retracing the evolutionary path of the FSY1 gene brought to light an unparalleled number of independent HGT events involving a single fungal gene. We propose that the turbulent evolutionary history of the gene may be linked to the unique biochemical properties of the encoded transporter, whose predictable effect on fitness may be highly variable. In general, our results support the most recent views suggesting that inter-species HGT may have contributed much more substantially to shape fungal genomes than heretofore assumed.
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