Evidence map›Paper›PMID 23818534›Full record

SynthesisThe British journal of psychiatry : the journal of mental science2013

Socioeconomic status as a risk factor for dementia death: individual participant meta-analysis of 86 508 men and women from the UK.

Tom C Russ, Emmanuel Stamatakis, Mark Hamer, John M Starr, Mika Kivimäki, G David Batty

Abstract readMeta-Analysis
In one paragraph

Synthesis in The British journal of psychiatry : the journal of mental science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Genetic and environmental risk factors for dementia in African adults: A systematic review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tom C RussAlzheimer Scotland Dementia Research Centre, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK. tom.russ@nhs.net
Emmanuel Stamatakis
Mark Hamer
John M Starr
Mika Kivimäki
G David Batty

Funding

Socioeconomic gradient in CHD in early old ageR01HL036310 · NHLBI · UNIVERSITY OF LONDON · PI KIVIMAKI, MIKA J, MARMOT, MICHAEL G · 1986 to 2012
$3.1M
Health behaviors over the adult lifecourse and cognitive agingR01AG034454 · NIA · UNIVERSITY COLLEGE LONDON · PI KIVIMAKI, MIKA J, SINGH-MANOUX, ARCHANA · 2009 to 2013
$1.5M
British Heart Foundation RG/13/2/30098Medical Research Council G0700704Medical Research Council MR/K026992/1NHLBI NIH HHS R01 HL036310NHLBI NIH HHS R01HL036310NIA NIH HHS R01 AG034454NIA NIH HHS R01AG034454Wellcome Trust
6 · The paper itself

Abstract

backgroundLife-course socioeconomic factors may have a role in dementia aetiology but there is a current paucity of studies. Meta-analyses of individual participant data would considerably strengthen this evidence base.

aimsTo examine the association between socioeconomic status in early life and adulthood with later dementia death.

methodIndividual participant meta-analysis of 11 prospective cohort studies (1994-2004, n = 86 508).

resultsLeaving full-time education at an earlier age was associated with an increased risk of dementia death in women (fully adjusted hazard ratio (HR) for age ≤14 v. age ≥16: HR = 1.76, 95% CI 1.23-2.53) but not men. Occupational social class was not statistically significantly associated with dementia death in men or women.

conclusionsLower educational attainment in women was associated with an increased risk of dementia-related death independently of common risk behaviours and comorbidities.

Indexed as

Social ClassDementiaEducational StatusFemaleHealth BehaviorHealth SurveysHumansMalePrognosisRisk FactorsRisk-TakingSmokingSocioeconomic FactorsUnited Kingdom

Identifiers

PMID23818534
PMCPMC3696876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.