Evidence map›Paper›PMID 23818287›Full record

ArticleEuropean journal of preventive cardiology2014

Interarm differences in systolic blood pressure and mortality among US army veterans: aetiological associations and risk prediction in the Vietnam Experience Study.

James White, Laust H Mortensen, Mika Kivimäki, Catharine R Gale, G David Batty

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in European journal of preventive cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Prevalence of systolic inter-arm differences in blood pressure for different primary care populations: systematic review and meta-analysis.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016
    Pooled it
  3. Inter-arm blood pressure difference and mortality: a cohort study in an asymptomatic primary care population at elevated cardiovascular risk.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016
    Trial
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  11. Systolic inter-arm blood pressure difference and risk of cognitive decline in older people: a cohort study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020
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  14. The interarm blood pressure difference: Do we know enough yet?Journal of clinical hypertension (Greenwich, Conn.) · 2017
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  15. Interarm blood pressure differences predict target organ damage in type 2 diabetes.Journal of clinical hypertension (Greenwich, Conn.) · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

James WhiteCardiff University, Cardiff, UK whitej11@cf.ac.uk.
Laust H MortensenUniversity of Copenhagen, Copenhagen, The Netherlands.
Mika KivimäkiUniversity College London, London, UK.
Catharine R GaleUniversity of Southampton, Southampton, UK.
G David BattyUniversity College London, London, UK.
University College London · GBCardiff University · GBUniversity of Southampton · GB

Funding

British Heart FoundationCancer Research UKMedical Research Council G0400491Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_UP_A620_1014Medical Research Council MC_UP_A620_1015Medical Research Council MC_UU_12011/1Medical Research Council MC_UU_12011/2Medical Research Council MR/K026992/1Wellcome Trust WT087640MA
6 · The paper itself

Abstract

backgroundDifferences between the arms in systolic blood pressure (SBP) of ≥10 mmHg have been associated with an increased risk of mortality in patients with hypertensive and chronic renal disease. For the first time, we examined these relationships in a non-clinical population.

designCohort study.

methodsParticipants were 4419 men (mean age 38.37 years) from the Vietnam Experience Study. Bilateral SBP and diastolic BP (DBP), serum lipids, fasting glucose, erythrocyte sedimentation rate, metabolic syndrome, and ankle brachial index were assessed in 1986.

resultsTen per cent of men had an interarm difference of ≥10 and 2.4% of ≥15 mmHg. A 15-year follow-up period gave rise to 246 deaths (64 from cardiovascular disease, CVD). Interarm differences of ≥10 mmHg were associated with an elevated risk of all-cause mortality (hazard ratio, HR, 1.49, 95% confidence interval, CI, 1.04-2.14) and CVD mortality (HR 1.93, 95% CI 1.01-3.69). After adjusting for SBP, DBP, lipids, fasting glucose, and erythrocyte sedimentation rate, associations between interarm differences of ≥10 mmHg and all-cause mortality (HR 1.35, 95% CI 0.94-1.95) and CVD mortality (1.62, 95% CI 0.84-3.14) were significantly attenuated.

conclusionsIn this non-clinical cohort study, interarm differences in SBP were not associated with mortality after accounting for traditional CVD risk factors. Interarm differences might not be valuable as an additional risk factor for mortality in populations with a low risk of CVD.

Indexed as

Blood PressureVeterans HealthVietnam ConflictAdultAnkle Brachial IndexBiomarkersBlood GlucoseBlood SedimentationFemaleHumansHypertensionLipidsMalePredictive Value of TestsPrognosisProportional Hazards ModelsBiomarkersBlood GlucoseLipidsEpidemiologyhypertensionrisk factors

Identifiers

PMID23818287
PMCPMC3805466
OpenAlexW2100116877

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.