Evidence map›Paper›PMID 23817796›Full record

ReviewPhysiology (Bethesda, Md.)2013

Role of β-adrenergic receptors and nitric oxide signaling in exercise-mediated cardioprotection.

John W Calvert, David J Lefer

Open access · greenAbstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Subcellular Localization Guides eNOS Function.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Ultra-Endurance Participation and Acute Kidney Injury: A Narrative Review.International journal of environmental research and public health · 2022
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Mechanisms of exercise-induced cardioprotection.Physiology (Bethesda, Md.) · 2014
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

John W CalvertDepartment of Surgery, Division of Cardiothoracic Surgery, Carlyle Fraser Heart Center, Emory University School of Medicine, Atlanta, Georgia, USA. dlefer@emory.edu
David J Lefer
Emory University · US

Funding

Preclinical Consortium to Facilitate Translation of Cardioprotective TherapiesU24HL094373 · NHLBI · UNIVERSITY OF LOUISVILLE · PI BOLLI, ROBERTO · 2010 to 2014
$9.6M
Functional Cardio-MetabolomicsP20HL113452 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI HAZEN, STANLEY L, TANG, WAI HONG WILSON · 2012 to 2016
$4.8M
Cardioprotective Actions of Hydrogen SulfideR01HL092141 · NHLBI · LSU HEALTH SCIENCES CENTER · PI LEFER, DAVID JOSEPH · 2009 to 2013
$1.9M
Hydrogen sulfide attenuates heart failure through Nrf2-mediated signalingR01HL098481 · NHLBI · EMORY UNIVERSITY · PI CALVERT, JOHN WINTER · 2010 to 2014
$1.9M
Nitrite Mediated CardioprotectionR01HL093579 · NHLBI · LSU HEALTH SCIENCES CENTER · PI LEFER, DAVID JOSEPH · 2009 to 2012
$1.5M
NHLBI NIH HHS 1P20 HL-113452NHLBI NIH HHS 1U24 HL-094373NHLBI NIH HHS 5R01 HL-092141NHLBI NIH HHS 5R01 HL-093579NHLBI NIH HHS 5R01 HL-098481NHLBI NIH HHS P20 HL113452NHLBI NIH HHS R01 HL092141NHLBI NIH HHS R01 HL093579NHLBI NIH HHS R01 HL098481NHLBI NIH HHS U24 HL094373
6 · The paper itself

Abstract

Exercise promotes cardioprotection in both humans and animals not only by reducing risk factors associated with cardiovascular disease but by reducing myocardial infarction and improving survival following ischemia. This article will define the role that nitric oxide and β-adrenergic receptors play in mediating the cardioprotective effects of exercise in the setting of ischemia-reperfusion injury.

Indexed as

AnimalsCardiovascular DiseasesDisease Models, AnimalDogsExerciseHumansMiceMyocardial InfarctionNitric OxidePhysical Conditioning, AnimalRatsReceptors, Adrenergic, betaReperfusion InjurySignal TransductionNitric OxideReceptors, Adrenergic, beta

Identifiers

PMID23817796
PMCPMC3742128
OpenAlexW2121001808

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.