ArticleAnnals of biomedical engineering2013
Topology of blood transport in the human left ventricle by novel processing of Doppler echocardiography.
Article in Annals of biomedical engineering, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 91 citations in OpenAlex.
- Hemodynamic Evaluation for Mitral Valve Replacement.Annals of biomedical engineering · 2026Article
- Flow transport and not ejection fraction determines blood stasis in patients with impaired left ventricular systolic function.Physiological reports · 2025Article
- Left ventricle diastolic vortex ring characterization in ischemic cardiomyopathy: insight into atrio-ventricular interplay.Medical & biological engineering & computing · 2024Article
- A Computational Investigation of the Effects of Temporal Synchronization of Left Ventricular Assist Device Speed Modulation with the Cardiac Cycle on Intraventricular Hemodynamics.Annals of biomedical engineering · 2024Article
- Benchtop Models of Patient-Specific Intraventricular Flow During Heart Failure and LVAD Support.Journal of biomechanical engineering · 2023Article
- Efficient multi-fidelity computation of blood coagulation under flow.PLoS computational biology · 2023Article
- Changes in blood flow vortices inside the left ventricle in COVID-19 patients with intraventricular clot despite a normal coronary and myocardial motion.Journal of echocardiography · 2023Article
- Assessment of Blood Flow Transport in the Left Ventricle Using Ultrasound. Validation Against 4-D Flow Cardiac Magnetic Resonance.Ultrasound in medicine & biology · 2022Article
- Non-Newtonian blood rheology impacts left atrial stasis in patient-specific simulations.International journal for numerical methods in biomedical engineering · 2022Article
- Understanding the influence of left ventricular assist device inflow cannula alignment and the risk of intraventricular thrombosis.Biomedical engineering online · 2021Article
- Cardiac Kinetic Energy and Viscous Dissipation Rate From Radial Flow Data.Frontiers in physiology · 2021Article
- Demonstration of Patient-Specific Simulations to Assess Left Atrial Appendage Thrombogenesis Risk.Frontiers in physiology · 2021Article
- Age-Dependence of Flow Homeostasis in the Left Ventricle.Frontiers in physiology · 2019Article
- A Re-Engineered Software Interface and Workflow for the Open-Source SimVascular Cardiovascular Modeling Package.Journal of biomechanical engineering · 2018Article
- Left ventricular hemodynamic forces as a marker of mechanical dyssynchrony in heart failure patients with left bundle branch block.Scientific reports · 2017Article
- Clinical assessment of intraventricular blood transport in patients undergoing cardiac resynchronization therapy.Meccanica · 2017Article
- Spatial phenotyping of the endocardial endothelium as a function of intracardiac hemodynamic shear stress.Journal of biomechanics · 2017Article
- Patient-specific modeling of left ventricular electromechanics as a driver for haemodynamic analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2016Article
- A clinical method for mapping and quantifying blood stasis in the left ventricle.Journal of biomechanics · 2016Article
- Integrated Regional Cardiac Hemodynamic Imaging and RNA Sequencing Reveal Corresponding Heterogeneity of Ventricular Wall Shear Stress and Endocardial Transcriptome.Journal of the American Heart Association · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Novel processing of Doppler-echocardiography data was used to study blood transport in the left ventricle (LV) of six patients with dilated cardiomyopathy and six healthy volunteers. Bi-directional velocity field maps in the apical long axis of the LV were reconstructed from color-Doppler echocardiography. Resulting velocity field data were used to perform trajectory-based computation of Lagrangian coherent structures (LCS). LCS were shown to reveal the boundaries of blood injected and ejected from the heart over multiple beats. This enabled qualitative and quantitative assessments of blood transport patterns and residence times in the LV. Quantitative assessments of stasis in the LV are reported, as well as characterization of LV vortex formations from E-wave and A-wave filling.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.