Evidence map›Paper›PMID 23817548›Full record

ArticleNature neuroscience2013

Bidirectional effects of aversive learning on perceptual acuity are mediated by the sensory cortex.

Mark Aizenberg, Maria Neimark Geffen

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Nature neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

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  15. Human Sensory Cortex Contributes to the Long-Term Storage of Aversive Conditioning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mark AizenbergDepartment of Otorhinolaryngology and Head and Neck Surgery, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Maria Neimark Geffen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although emotional learning affects sensory acuity, little is known about how these changes are facilitated in the brain. We found that auditory fear conditioning in mice elicited either an increase or a decrease in frequency discrimination acuity depending on how specific the learned response was to the conditioned tone. Using reversible pharmacological inactivation, we found that the auditory cortex mediated learning-evoked changes in acuity in both directions.

Indexed as

Acoustic StimulationAmygdalaAnimalsAuditory CortexAuditory ThresholdAvoidance LearningConditioning, ClassicalCuesDifferential ThresholdDiffusionDiscrimination, PsychologicalElectroshockFearFluorescent DyesMaleMiceFluorescent DyesMuscimol

Identifiers

PMID23817548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.