ArticleThe American journal of tropical medicine and hygiene2013
Sequence analyses of 2012 West Nile virus isolates from Texas fail to associate viral genetic factors with outbreak magnitude.
Article in The American journal of tropical medicine and hygiene, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- A systematic review of spatial decision support systems in public health informatics supporting the identification of high risk areas for zoonotic disease outbreaks.International journal of health geographics · 2018Pooled it
- Article
- On the Fly: Interactions Between Birds, Mosquitoes, and Environment That Have Molded West Nile Virus Genomic Structure Over Two Decades.Journal of medical entomology · 2019Review
- Estimating the Health-Related Costs of 10 Climate-Sensitive U.S. Events During 2012.GeoHealth · 2019Article
- Comparative fitness of West Nile virus isolated during California epidemics.PLoS neglected tropical diseases · 2019Article
- The rise of neglected tropical diseases in the "new Texas".PLoS neglected tropical diseases · 2018Review
- Dynamics of West Nile virus evolution in mosquito vectors.Current opinion in virology · 2016Review
- Virulence and Evolution of West Nile Virus, Australia, 1960-2012.Emerging infectious diseases · 2016Article
- Genetic Variability of West Nile Virus in U.S. Blood Donors from the 2012 Epidemic Season.PLoS neglected tropical diseases · 2016Article
- West Nile Virus Encephalitis 16 Years Later.Brain pathology (Zurich, Switzerland) · 2015Review
- Comparing competitive fitness of West Nile virus strains in avian and mosquito hosts.PloS one · 2015Article
- Evidence for co-evolution of West Nile Virus and house sparrows in North America.PLoS neglected tropical diseases · 2014Article
- West Nile virus isolated from a Virginia opossum (Didelphis virginiana) in northwestern Missouri, USA, 2012.Journal of wildlife diseases · 2014Article
- Current developments in understanding of West Nile virus central nervous system disease.Current opinion in neurology · 2014Review
- Towards an early warning system for forecasting human west nile virus incidence.PLoS currents · 2014Article
- Towards an early warning system for forecasting human west nile virus incidence.PLoS currents · 2014Article
- Co-circulation of West Nile virus variants, Arizona, USA, 2010.Emerging infectious diseases · 2014Article
- Lack of evidence of increased West Nile virus disease severity in the United States in 2012.The American journal of tropical medicine and hygiene · 2014Article
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7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 2012, Texas experienced the largest outbreak of human West Nile encephalitis (WNE) since the introduction of West Nile virus (WNV) in 2002. Despite the large number of WNV infections, data indicated the rate of reported WNE among human cases was no higher than in previous years. To determine whether the increase in WNV human cases could have been caused by viral genetic changes, the complete genomes of 17 isolates made from mosquito pools in Dallas and Montgomery Counties in 2012 were sequenced. The 2012 Texas isolates were found to be composed of two distinct clades, both circulating in Dallas and Montgomery Counties despite a 5-fold higher disease incidence in the former. Although minor genetic differences existed between Dallas and Montgomery WNV populations, there was weak support for population subdivision or adaptive changes. On the basis of these data, alternative explanations for increased WNV disease incidence in 2012 are proposed.
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