Evidence map›Paper›PMID 23816985›Full record

ArticleClinical breast cancer2013

The validity and utility of the M. D. Anderson Symptom Inventory in patients with breast cancer: evidence from the symptom outcomes and practice patterns data from the eastern cooperative oncology group.

Tito R Mendoza, Fengmin Zhao, Charles S Cleeland, Lynne I Wagner, Linda J Patrick-Miller, Michael J Fisch

Abstract readValidation Study
In one paragraph

Article in Clinical breast cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Trial
  2. Effects of exercise during chemotherapy on chemotherapy-induced peripheral neuropathy: a multicenter, randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
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  10. Validation of the Skin Symptom Assessment (SSA) questionnaire for the evaluation of radiation dermatitis in breast cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  11. Article
  12. Review
  13. Observational
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tito R MendozaDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX. Electronic address: tmendoza@mdanderson.org.
Fengmin Zhao
Charles S Cleeland
Lynne I Wagner
Linda J Patrick-Miller
Michael J Fisch

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Foreign Accrual - ECOGU10CA037403 · NCI · UNIVERSITY OF WISCONSIN MADISON · PI COMIS, ROBERT L · 1985 to 2014
$34.6M
Developing an Oncology Workforce for the 21st Century - Renewal 01K12CA139160 · NCI · UNIVERSITY OF CHICAGO · PI OLOPADE, OLUFUNMILAYO F., SMITH, SONALI · 2010 to 2024
$10.6M
Reducing the Symptom Burden Produced by Aggressive Cancer TherapiesR01CA026582 · NCI · UNIVERSITY OF WISCONSIN MADISON · PI CLEELAND, CHARLES S · 1986 to 2013
$7.3M
ECOG Clinical TrialsU10CA017145 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BENSON, AL B · 1985 to 2013
$6.1M
Participation in the Eastern Cooperative Oncology GroupU10CA107868 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI AISNER, JOSEPH · 2004 to 2013
$2.3M
NCI NIH HHS K12 CA139160NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA026582NCI NIH HHS U10 CA017145NCI NIH HHS U10 CA037403NCI NIH HHS U10 CA107868NCI NIH HHS U10 CA17145NCI NIH HHS U10 CA37403
6 · The paper itself

Abstract

backgroundThe M. D. Anderson Symptom Inventory (MDASI) is a psychometrically validated patient-reported outcome measurement that assesses the severity and impact of multiple symptoms related to cancer and its treatment. With the MDASI, patients rate 13 common "core" symptoms and 6 items that reflect symptom interference with functioning. Several MDASI modules (core symptom and interference items plus additional symptoms specific to a particular cancer type or treatment modality) have been developed. Although the original MDASI validation study encompassed various cancer types, the instrument's psychometric properties have not been examined in a homogenous sample of patients with breast cancer in a national multicenter study. MATERIALS AND

methodsWe performed a secondary analysis of data from an Eastern Cooperative Oncology Group study to establish the reliability, validity, and sensitivity of the MDASI in a large sample of patients with breast cancer (n = 1544), 78% of whom were receiving treatment. The instrument was administered twice, approximately 1 month apart.

resultsInternal consistency and test-retest reliability were adequate, with Cronbach α values ≥ 0.85 and intraclass correlations ≥ 0.76 for all subscales. Known-group validity was evaluated by using performance status, tumor response, and disease stage. Sensitivity to change in patient-reported quality of life was established.

conclusionThe MDASI is a valid, reliable, and sensitive symptom-assessment instrument that can enhance descriptive and clinical studies of symptom status in patients with breast cancer. Future studies might include cognitive debriefing and qualitative interviews to identify additional disease-specific items for inclusion in a MDASI breast cancer module.

Indexed as

Surveys and QuestionnairesAdolescentAdultAgedAged, 80 and overAlgorithmsBreast NeoplasmsBreast Neoplasms, MaleChecklistFemaleHumansMaleMiddle AgedPredictive Value of TestsProfessional PracticePrognosisEastern Cooperative Oncology GroupM. D. Anderson Symptom InventoryPatient-reported outcomeSymptom assessmentValidation

Identifiers

PMID23816985
PMCPMC3775936

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.