ArticlePathogens and global health2013
Prevalence of Toxoplasma gondii infection among individuals with severe mental illness in Nigeria: a case control study.
Article in Pathogens and global health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Human Toxoplasma gondii infection in Nigeria: a systematic review and meta-analysis of data published between 1960 and 2019.BMC public health · 2020Pooled it
- Meta-Analysis of Anti-Toxoplasma gondii IgM Antibodies in Acute Psychosis.Schizophrenia bulletin · 2015Pooled it
- Prevalence ofMicroorganisms · 2024Article
- Global seroprevalence ofHealth science reports · 2023Article
- Prevalence and Predictors ofFrontiers in psychiatry · 2022Article
- Is latent Toxoplasma gondii infection associated with the occurrence of schizophrenia? A case-control study.PloS one · 2022Article
- Shedding proportion ofParasite epidemiology and control · 2020Article
- Sero-prevalence of Toxoplasma gondii and associated risk factors among psychiatric outpatients attending University of Gondar Hospital, Northwest Ethiopia.BMC infectious diseases · 2019Article
- A Case-Control Seroprevalence Study on the Association BetweenFrontiers in psychiatry · 2019Article
- Prevalence of malaria, typhoid, toxoplasmosis and rubella among febrile children in Cameroon.BMC infectious diseases · 2016Article
- High seroprevalence of Toxoplasma gondii infection in inmates: A case control study in Durango City, Mexico.European journal of microbiology & immunology · 2014Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile the aetiology for most psychotic disorders is unknown, a strong association has been observed between Toxoplasma gondii infection and psychosis. The proportion of individuals with psychotic disorders who have current or past infection with toxoplasma has been varied. Reports from the African continent have however been scanty.
methodsA case control study of patients with a psychotic disorder presenting for the first time to a regional psychiatric facility was undertaken and compared to age and sex-matched healthy controls. In addition to socio-demographic and clinical characteristics, seroprevalence (IgG and IgM) of T. gondii was undertaken using an immunoassay test kit.
resultsIgG seropositivity was significantly higher among cases (30·7% vs 17·85%, OR = 2·04, 95% CI = 1·12-3·74, P<0·02). In contrast, IgM seropositivity was significantly lower among the cases (7·14% vs 8·57%, OR = 0·82, 95% CI = 0·31-2·16, P = 0·82). Cases who were IgG seropositive to T. gondii were more likely to be older (P<0·001) and female (P<0·001). There was no statistically significant difference in terms of T. gondii infection and, eaten poorly cooked meat (0·88), and diagnostic group (P = 0·53). Though there was a trend towards exposure to cats, this failed to reach significance (P = 0·08).
conclusionT. gondii (IgG) infection is common among individuals with severe mental illness sampled and significantly higher compared to controls.
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