Evidence map›Paper›PMID 23816063›Full record

ArticleClinical and translational allergy2013

Health-related quality of life, assessed with a disease-specific questionnaire, in Swedish adults suffering from well-diagnosed food allergy to staple foods.

Sven-Arne Jansson, Marianne Heibert-Arnlind, Roelinde Jm Middelveld, Ulf J Bengtsson, Ann-Charlotte Sundqvist, Ingrid Kallström-Bengtsson, Birgitta Marklund, Georgios Rentzos, Johanna Åkerström, Eva Östblom and 2 more

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational allergy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 38 citations in OpenAlex.

  1. The hidden price of food allergy: Understanding the social and financial burdens on families.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Review
  2. Article
  3. Article
  4. Peanut, soy, and emerging legume allergy in Canada.The journal of allergy and clinical immunology. Global · 2022
    Article
  5. [Influence of nut and peanut allergy on the quality of life of adults].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2022
    Review
  6. Article
  7. Food allergy-related concerns during the transition to self-management.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Quality of life in patients with food allergy.Clinical and molecular allergy : CMA · 2016
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Sven-Arne Jansson *The Centre for Allergy Research, Karolinska Institutet, P.O. Box 287, 17177, Stockholm, Sweden.
Marianne Heibert-Arnlind *Swedish Council on Health Technology Assessment, SBU, Stockholm, Sweden.
Roelinde Jm MiddelveldThe Centre for Allergy Research, Karolinska Institutet, P.O. Box 287, 17177, Stockholm, Sweden.
Ulf J BengtssonAllergy Unit, Sahlgrenska University Hospital, Gothenburg, Sweden.
Ann-Charlotte SundqvistSachs' Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden.
Ingrid Kallström-BengtssonThe Swedish Asthma and Allergy Foundation, Stockholm, Sweden.
Birgitta MarklundDepartment of Health and Caring Sciences, Linnaeus University, Kalmar, Sweden.
Georgios RentzosAllergy Unit, Sahlgrenska University Hospital, Gothenburg, Sweden.
Johanna ÅkerströmAllergy Unit, Sahlgrenska University Hospital, Gothenburg, Sweden.
Eva ÖstblomSachs' Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden.
Sven-Erik DahlénThe Centre for Allergy Research, Karolinska Institutet, P.O. Box 287, 17177, Stockholm, Sweden.
Staffan AhlstedtThe Centre for Allergy Research, Karolinska Institutet, P.O. Box 287, 17177, Stockholm, Sweden.
Karolinska Institutet · SESahlgrenska University Hospital · SELinnaeus University · SESachs' Children and Youth Hospital · SEStockholm South General Hospital · SESwedish Asthma and Allergy Association · SESwedish Council on Technology Assessment in Health Care · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur aim was to investigate the factors that affect health related quality of life (HRQL) in adult Swedish food allergic patients objectively diagnosed with allergy to at least one of the staple foods cow's milk, hen's egg or wheat. The number of foods involved, the type and severity of symptoms, as well as concomitant allergic disorders were assessed.

methodsThe disease-specific food allergy quality of life questionnaire (FAQLQ-AF), developed within EuroPrevall, was utilized. The questionnaire had four domains: Allergen Avoidance and Dietary Restrictions (AADR), Emotional Impact (EI), Risk of Accidental Exposure (RAE) and Food Allergy related Health (FAH). Comparisons were made with the outcome of the generic questionnaire EuroQol Health Questionnaire, 5 Dimensions (EQ-5D). The patients were recruited at an outpatient allergy clinic, based on a convincing history of food allergy supplemented by analysis of specific IgE to the foods in question. Seventy-nine patients participated (28 males, 51 females, mean-age 41 years).

resultsThe domain with the most negative impact on HRQL was AADR, assessing the patients' experience of dietary restrictions. The domain with the least negative impact on HRQL was FAH, relating to health concerns due to the food allergy. One third of the patients had four concomitant allergic disorders, which had a negative impact on HRQL. Furthermore, asthma in combination with food allergy had a strong impact. Anaphylaxis, and particularly prescription of an epinephrine auto-injector, was associated with low HRQL. These effects were not seen using EQ-5D. Analyses of the symptoms revealed that oral allergy syndrome and cardiovascular symptoms had the greatest impact on HRQL. In contrast, no significant effect on HRQL was seen by the number of food allergies.

conclusionsThe FAQLQ-AF is a valid instrument, and more accurate among patients with allergy to staple foods in comparison to the commonly used generic EQ-5D. It adds important information on HRQL in food allergic adults. We found that the restrictions imposed on the patients due to the diet had the largest negative impact on HRQL. Both severity of the food allergy and the presence of concomitant allergic disorders had a profound impact on HRQL.

Indexed as

AdultsFood allergyHealth-related quality of lifeInstrumentQuestionnaire

Identifiers

PMID23816063
PMCPMC3702411
OpenAlexW2147845589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.