ArticleThe journal of headache and pain2013
Migraine and periodic limb movement disorders in sleep in children: a preliminary case-control study.
Article in The journal of headache and pain, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Normal polysomnography parameters in healthy children: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- Sleep macro- and microstructure in migraine and cluster headache: a systematic review of objective assessments.The journal of headache and pain · 2026Pooled it
- Subjective Sleep Quality and Sleep Architecture in Patients With Migraine: A Meta-analysis.Neurology · 2021Pooled it
- Article
- Polysomnographic and clinical characteristics of sleep apnea headache patients.Sleep & breathing = Schlaf & Atmung · 2024Article
- The complexities of the sleep-pain relationship in adolescents: A critical review.Sleep medicine reviews · 2023Review
- How to Assess the Headache-Sleep Disorders Comorbidity in Children and Adolescents.Journal of clinical medicine · 2021Review
- Sleep Disorders in Pediatric Migraine: A Questionnaire-Based Study.Journal of clinical medicine · 2021Article
- Sleep Deficiency and Pediatric Chronic Pain.The Nursing clinics of North America · 2021Review
- Changes in headache characteristics with oral appliance treatment for obstructive sleep apnea.Scientific reports · 2021Article
- The Interrelationship between Sleep and Chronic Pain in Adolescents.Current opinion in physiology · 2019Article
- Linking Traumatic Brain Injury, Sleep Disruption and Post-Traumatic Headache: a Potential Role for Glymphatic Pathway Dysfunction.Current pain and headache reports · 2019Review
- Restless legs syndrome/Willis-Ekbom disease prevalence in beta thalassemia patients.Sleep & breathing = Schlaf & Atmung · 2018Article
- Article
- Altered Brain Functional Connectome in Migraine with and without Restless Legs Syndrome: A Resting-State Functional MRI Study.Frontiers in neurology · 2018Article
- Periodic limb movements in sleep are followed by increases in EEG activity, blood pressure, and heart rate during sleep.Sleep & breathing = Schlaf & Atmung · 2017Article
- Visual-spatial training efficacy in children affected by migraine without aura: a multicenter study.Neuropsychiatric disease and treatment · 2017Article
- The Rorschach Test Evaluation in Chronic Childhood Migraine: A Preliminary Multicenter Case-Control Study.Frontiers in neurology · 2017Article
- Sleep and Pain in Pediatric Illness: A Conceptual Review.CNS neuroscience & therapeutics · 2016Review
- Associations Between Sleep Quality and Migraine Frequency: A Cross-Sectional Case-Control Study.Medicine · 2016Observational
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationships between sleep and headaches are complex and manifold. About the variety of phenomena that can disrupt the sleep macrostructure and can impact its restorative function, the periodic limb movements disorder (PLMd) can be considered as the most powerful.No studies are known about the role of PLMd in the pathophysiology of migraine in children.Aim of study is to assess the prevalence of PLMd and migraine and their relationship with disability and pain intensity in a pediatric sample, referred for migraine without aura by pediatricians.
methodsAfter a preliminary sleep habits screening with the Sleep Disturbances Scale for Children, 34 migraine subjects affected by migraine without aura (20 M, 14 F) (mean age 9.08; SD ± 2.28) and 51 volunteers healthy children (28 M, 23 F) (mean age 9.37; SD ± 1.81) accepted to underwent overnight PSG recordings in the Sleep Laboratory of the Clinic of Child and Adolescent Neuropsychiatry, in order to define the macrostructural sleep characteristics and the prevalence of PLMd. Subsequently, the migraineurs sample was studied in order to define the relationship between disability, pain intensity, therapeutical responsiveness and the presence of PLMd.
resultsIn the migraineurs children group, the individuals with PLM pathological index (PLMI ≥ 5) represent the 26.47% of sample and present higher frequency (p < 0.001), intensity (p < 0.001), duration (p = 0.006) and life impairment as scored in the PedMIDAS (p < 0.001) of headache and lower efficacy of prophylactic (p = 0.001) and acute (p = 0.006) pharmacological treatment than MoA children without PLM pathological index.
conclusionsThis preliminary study indicates the potential value of the determination of the PLMd signs, and the importance of the PSG evaluation in children affected by migraine, particularly when the clinical and pharmacological management tend to fail in the attacks control.
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