ArticleNucleic acids research2013
Lighting up left-handed Z-DNA: photoluminescent carbon dots induce DNA B to Z transition and perform DNA logic operations.
Article in Nucleic acids research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 89 citations in OpenAlex.
- Interaction of Carbon Dots with Nucleic Acids Is Driven by Their Surface Charge.Journal of chemical information and modeling · 2026Article
- Assessing B-Z DNA Transitions in Solutions via Infrared Spectroscopy.Biomolecules · 2023Article
- Removal of eDNA from fabrics using a novel laundry DNase revealed using high-resolution imaging.Scientific reports · 2021Article
- Non-Canonical Helical Structure of Nucleic Acids Containing Base-Modified Nucleotides.International journal of molecular sciences · 2021Review
- Carbon Dots-Based Logic Gates.Nanomaterials (Basel, Switzerland) · 2021Review
- Organic dots (O-dots) for theranostic applications: preparation and surface engineering.RSC advances · 2021Review
- Endogenous Fluorescence Carbon Dots Derived from Food Items.Innovation (Cambridge (Mass.)) · 2020Review
- Chiral Self-Assembly of Porphyrins Induced by Chiral Carbon Dots.Frontiers in chemistry · 2020Article
- Growing prospects of DNA nanomaterials in novel biomedical applications.RSC advances · 2019Review
- Praseodymium promotes B-Z transition in self-assembled DNA nanostructures.RSC advances · 2019Article
- The Cucurbit[7]Uril-Based Supramolecular Chemistry for Reversible B/Z-DNA Transition.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2018Article
- Graphene-Based Materials for Biosensors: A Review.Sensors (Basel, Switzerland) · 2017Review
- Lanthanum induced B-to-Z transition in self-assembled Y-shaped branched DNA structure.Scientific reports · 2016Article
- Chemically induced fluorescence switching of carbon-dots and its multiple logic gate implementation.Scientific reports · 2015Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Left-handed Z-DNA has been identified as a transient structure occurred during transcription. DNA B-Z transition has attracted much attention because of not only Z-DNA biological importance but also their relation to disease and DNA nanotechnology. Recently, photoluminescent carbon dots, especially highly luminescent nitrogen-doped carbon dots, have attracted much attention on their applications to bioimaging and gene/drug delivery because of carbon dots with low toxicity, highly stable photoluminescence and controllable surface function. However, it is still unknown whether carbon dots can influence DNA conformation or structural transition, such as B-Z transition. Herein, based on our previous series work on DNA interactions with carbon nanotubes, we report the first example that photoluminescent carbon dots can induce right-handed B-DNA to left-handed Z-DNA under physiological salt conditions with sequence and conformation selectivity. Further studies indicate that carbon dots would bind to DNA major groove with GC preference. Inspired by carbon dots lighting up Z-DNA and DNA nanotechnology, several types of DNA logic gates have been designed and constructed based on fluorescence resonance energy transfer between photoluminescent carbon dots and DNA intercalators.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.