ReviewThe oncologist2013
A reappraisal of the diagnostic and therapeutic management of uncommon histologies of primary ocular adnexal lymphoma.
Review in The oncologist, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 43 citations in OpenAlex.
- From Inflammation to Malignancy: Diagnosing Ocular Adnexal Diffuse Large B-Cell Lymphoma Beyond Dacryocystitis.Cureus · 2026Article
- Ocular adnexa follicular lymphoma: clinicopathological study of 23 patients.Virchows Archiv : an international journal of pathology · 2026Article
- Construction and validation of a novel web-based nomogram for primary ocular adnexal lymphoma: a real-world analysis based on the Surveillance, Epidemiology, and End Results database.Translational cancer research · 2024Article
- Primary central nervous system lymphoma.Nature reviews. Disease primers · 2023Review
- CD5-Negative Primary Mantle Cell Lymphoma Presenting with a Bilateral Conjunctival Mass: A Potential Diagnostic Pitfall.Current oncology (Toronto, Ont.) · 2023Article
- Primary lacrimal sac lymphoma: a case-based retrospective study in a Chinese population.International journal of ophthalmology · 2023Article
- A deep learning model combining multimodal radiomics, clinical and imaging features for differentiating ocular adnexal lymphoma from idiopathic orbital inflammation.European radiology · 2022Article
- [Lymphoma of the eye and its adnexa : Modern pathological diagnostics and systemic treatment].Die Ophthalmologie · 2022Review
- [Treatment and prognosis of primary ocular adnexal extranodal marginal zone mucosa-associated lymphoid tissue lymphoma: a report from a single center].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2022Article
- Clinical experience on diagnosis and treatment for malignancy originating from the dacryocyst.Eye (London, England) · 2018Article
- Ocular adnexal marginal zone lymphoma of mucosa-associated lymphoid tissue.Clinical and experimental medicine · 2018Review
- Establishment of a combination scoring method for diagnosis of ocular adnexal lymphoproliferative disease.PloS one · 2017Article
- A Primary Bone Diffuse Large B-Cell Lymphoma with Ocular Adnexal Involvement.Turkish journal of haematology : official journal of Turkish Society of Haematology · 2016Article
- Conjunctival lymphoma: case report.Romanian journal of ophthalmologyArticle
- Conjunctival follicular lymphoma after treatment for invasive squamous cell carcinoma.Case reports in ophthalmologyArticle
- Ocular adnexal lymphoma: A single-institution retrospective study.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lymphoma is the most common malignancy arising in the ocular adnexa, which includes conjunctiva, lachrymal gland, lachrymal sac, eyelids, orbit soft tissue, and extraocular muscles. Ocular adnexal lymphoma (OAL) accounts for 1%-2% of non-Hodgkin lymphoma and 5%-15% of extranodal lymphoma. Histology, stage, and primary localizations are the most important variables influencing the natural history and therapeutic outcome of these malignancies. Among the various lymphoma variants that could arise in the ocular adnexa, marginal zone B-cell lymphoma (OA-MZL) is the most common one. Other types of lymphoma arise much more rarely in these anatomical sites; follicular lymphoma is the second most frequent histology, followed by diffuse large B-cell lymphoma and mantle cell lymphoma. Additional lymphoma entities, like T-cell/natural killer cell lymphomas and Burkitt lymphoma, only occasionally involve orbital structures. Because they are so rare, related literature mostly consists of anecdotal cases included within series focused on OA-MZL and sporadic case reports. This bias hampers a global approach to clinical and molecular properties of these types of lymphoma, with a low level of evidence supporting therapeutic options. This review covers the prevalence, clinical presentation, behavior, and histological and molecular features of uncommon forms of primary OAL and provides practical recommendations for therapeutic management.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.