ArticleMagnetic resonance in medicine2013
T₁ estimation for aqueous iron oxide nanoparticle suspensions using a variable flip angle SWIFT sequence.
Article in Magnetic resonance in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Fast Compressed Sensing of 3D Radial TJournal of imaging · 2023Article
- Preparation of Scalable Silica-Coated Iron Oxide Nanoparticles for Nanowarming.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Establishing the overlap of IONP quantification with echo and echoless MR relaxation mapping.Magnetic resonance in medicine · 2018Article
- Positive contrast from cells labeled with iron oxide nanoparticles: Quantitation of imaging data.Magnetic resonance in medicine · 2017Article
- Investigation of the Longitudinal Relaxation Time of Rat Tibial Cortical Bone Using SWIFT.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2017Article
- Quantification and biodistribution of iron oxide nanoparticles in the primary clearance organs of mice using TMagnetic resonance in medicine · 2017Article
- Imaging and quantification of iron-oxide nanoparticles (IONP) using MP-RAGE and UTE based sequences.Magnetic resonance in medicine · 2017Article
- A comprehensive literatures update of clinical researches of superparamagnetic resonance iron oxide nanoparticles for magnetic resonance imaging.Quantitative imaging in medicine and surgery · 2017Review
- Image-guided thermal therapy with a dual-contrast magnetic nanoparticle formulation: A feasibility study.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2016Article
- Tracking and Quantification of Magnetically Labeled Stem Cells using Magnetic Resonance Imaging.Advanced functional materials · 2016Article
- In Vitro/In Vivo Toxicity Evaluation and Quantification of Iron Oxide Nanoparticles.International journal of molecular sciences · 2015Review
- Quantitative contrast-enhanced MRI with superparamagnetic nanoparticles using ultrashort time-to-echo pulse sequences.Magnetic resonance in medicine · 2015Article
- Measurement of TMagnetic resonance in medicine · 2015Article
- 3D Cine Magnetic Resonance Imaging of Rat Lung ARDS using Gradient-modulated SWIFT with Retrospective Respiratory Gating.Proceedings of SPIE--the International Society for Optical Engineering · 2015Article
- Accounting for biological aggregation in heating and imaging of magnetic nanoparticles.Technology · 2014Article
- Quantifying iron-oxide nanoparticles at high concentration based on longitudinal relaxation using a three-dimensional SWIFT Look-Locker sequence.Magnetic resonance in medicine · 2014Article
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5 authors.
Funding
Abstract
purposeT1 quantification of contrast agents, such as super-paramagnetic iron oxide nanoparticles, is a challenging but important task inherent to many in vivo applications in magnetic resonance imaging. In this work, a sweep imaging with Fourier transformation using variable flip angles (VFAs-SWIFT) method was proposed to measure T1 of aqueous super-paramagnetic iron oxide nanoparticle suspensions.
methodsT1 values of various iron concentrations (from 1 to 7 mM) were measured using VFA-SWIFT and three-dimensional spoiled gradient-recalled echo with VFAs (VFA-SPGR) sequences on a 7 T MR scanner. For validation, T1 values were also measured using a spectroscopic inversion-recovery sequence on a 7 T spectrometer.
resultsVFA-SWIFT demonstrated its advantage for quantifying T1 of highly concentrated aqueous super-paramagnetic iron oxide nanoparticle suspensions, but VFA-SPGR failed at the higher end of iron concentrations. Both VFA-SWIFT and VFA-SPGR yielded linear relationships between the relaxation rate and iron concentrations, with relaxivities of 1.006 and 1.051 s(-1) mM(-1) at 7 T, respectively, in excellent agreement with the spectroscopic measurement of 1.019 s(-1) mM(-1) .
conclusionVFA-SWIFT is able to achieve accurate T1 quantification of aqueous super-paramagnetic iron oxide nanoparticle suspensions up to 7 mM.
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