Evidence map›Paper›PMID 23813826›Full record

ReviewJournal of feline medicine and surgery2013

Cryptococcosis in cats: ABCD guidelines on prevention and management.

Maria Grazia Pennisi, Katrin Hartmann, Albert Lloret, Lluis Ferrer, Diane Addie, Sándor Belák, Corine Boucraut-Baralon, Herman Egberink, Tadeusz Frymus, Tim Gruffydd-Jones and 8 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of feline medicine and surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. A novel case of feline Exophiala spinifera disease in Americas: review integrating diagnosis and clinical.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Review
  6. What Do We Know AboutJournal of fungi (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Feline Cryptococcosis due toCase reports in veterinary medicine · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. First report of oral cryptococcal osteomyelitis in a cat.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  13. Article
  14. Article
  15. Insight into the Role of Psychological Factors in Oral Mucosa Diseases.International journal of molecular sciences · 2022
    Review
  16. Article
  17. Isolation ofMedical mycology case reports · 2019
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Maria Grazia PennisiEuropean Advisory Board on Cat Diseases. pennipet@unime.it
Katrin Hartmann
Albert Lloret
Lluis Ferrer
Diane Addie
Sándor Belák
Corine Boucraut-Baralon
Herman Egberink
Tadeusz Frymus
Tim Gruffydd-Jones
Margaret J Hosie
Hans Lutz
Fulvio Marsilio
Karin Möstl
Alan D Radford
Etienne Thiry
Uwe Truyen
Marian C Horzinek
University of Liège · BE

Funding

Biotechnology and Biological Sciences Research Council BB/D008425/1Medical Research Council G0300387
6 · The paper itself

Abstract

overviewCryptococcosis is worldwide the most common systemic fungal disease in cats; it is caused by the Cryptococcus neoformans- Cryptococcus gattii species complex, which includes eight genotypes and some subtypes (strains) with varying geographical distribution, pathogenicity and antimicrobial susceptibility. Cats acquire the infection from a contaminated environment. The prognosis is favourable in most cases, provided a diagnosis is obtained sufficiently early and prolonged treatment is maintained. INFECTION: Basidiospores are the infectious propagules of Cryptococcus species as they penetrate the respiratory system and induce primary infection. Asymptomatic colonisation of the respiratory tract is more common than clinical disease. Avian guanos, particularly pigeon droppings, offer favourable conditions for the reproduction of C neoformans. Both Cryptococcus species are associated with decaying vegetation. DISEASE SIGNS: Cryptococcosis caused by C neoformans or C gattii is indistinguishable clinically. The disease can present in nasal, central nervous system (which can derive from the nasal form or occur independently), cutaneous and systemic forms. DIAGNOSIS: An easy and reliable test for cryptococcosis diagnosis is antigen detection in body fluids. Only isolation and polymerase chain reaction allow identification of the species genotype. DISEASE MANAGEMENT: Amphotericin B, ketoconazole, fluconazole and itraconazole have all been used to treat cats. Surgical excision of any nodules in the skin, nasal or oral mucosa assists recovery. Continued treatment is recommended until the antigen test is negative. PREVENTION: Efficient preventive measures have not been demonstrated. Vaccines are not available.

Indexed as

AnimalsAntifungal AgentsCat DiseasesCatsCryptococcosisAntifungal Agents

Identifiers

PMID23813826
PMCPMC11148960
OpenAlexW1985458547

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.