ArticleClinical journal of the American Society of Nephrology : CJASN2013
The unjustified classification of kidney donors as patients with CKD: critique and recommendations.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Multidisciplinary care of kidney donation in Brugada syndrome: A case report.World journal of transplantation · 2025Article
- Consequences of low estimated glomerular filtration rate either before or early after kidney donation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024Article
- Risk Factors for Developing Low Estimated Glomerular Filtration Rate and Albuminuria in Living Kidney Donors.Kidney medicine · 2024Article
- Living kidney donors with HIV: experience and outcomes from a case series by the HOPE in Action Consortium.Lancet regional health. Americas · 2023Article
- Article
- Reclassification of CKD in living kidney donors with the refitted race-free eGFR formula.American journal of surgery · 2023Article
- Arterial Hypertension as a Risk Factor for Reduced Glomerular Filtration Rate after Living Kidney Donation.Journal of clinical medicine · 2020Article
- Postdonation eGFR and New-Onset Antihypertensive Medication Use After Living Kidney Donation.Transplantation direct · 2019Article
- Larger nephron size, low nephron number, and nephrosclerosis on biopsy as predictors of kidney function after donating a kidney.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019Article
- Interlaboratory Variability in Plasma Creatinine Measurement and the Relation with Estimated Glomerular Filtration Rate and Chronic Kidney Disease Diagnosis.Clinical journal of the American Society of Nephrology : CJASN · 2017Article
- Renal Function Profile in White Kidney Donors: The First 4 Decades.Journal of the American Society of Nephrology : JASN · 2016Article
- Living-Donor Kidney Transplantation: Reducing Financial Barriers to Live Kidney Donation--Recommendations from a Consensus Conference.Clinical journal of the American Society of Nephrology : CJASN · 2015Article
- Long-term medical risks to the living kidney donor.Nature reviews. Nephrology · 2015Review
- Gout after living kidney donation: correlations with demographic traits and renal complications.American journal of nephrology · 2015Article
- The consequences of chronic kidney disease mislabeling in living kidney donors.Mayo Clinic proceedings · 2014Article
- The Outcomes of Living Kidney Donation from Medically Complex Donors: Implications for the Donor and the Recipient.Current transplantation reports · 2014Article
- Transplantation: Increased ESRD and mortality risk for kidney donors?Nature reviews. Nephrology · 2014Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Unilateral nephrectomy for kidney donation results in loss of about 30% of baseline GFR, leaving some donors with GFR <60 ml/min per 1.73 m(2), the threshold for the diagnosis CKD. This has resulted in insurability problems for some donors. This article reviews the definition of CKD, risks associated with CKD, and large follow-up studies on the vital status and risk of ESRD in kidney donors. It also provides evidence that kidney donors, despite having reduced GFR, are not at increased risk for CKD-associated morbidity and mortality. Epidemiologic studies, most with follow-up <10 years, have shown an association between GFR <60 ml/min per 1.73 m(2) and higher mortality and progression to ESRD. Low GFR in the absence of any other markers for kidney disease, however, conveys attenuated or minimal risk. Of note, studies of long-term kidney donor outcomes (6-45 years) have not shown excess mortality or ESRD. The limitation of the collective evidence is that the increased risks associated with GFR <60 ml/min per 1.73 m(2) were demonstrated in much larger cohorts than those reported for kidney donor outcomes, but donor outcome studies have substantially longer follow-up. On the basis of current findings, kidney donors with low GFR and no other signs of kidney disease should not be classified as having CKD. This is definitely not the reward they deserve, and, more important, the implications of reduced GFR in donors are not associated with unfavorable outcomes.
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