Evidence map›Paper›PMID 23812892›Full record

Trial reportAIDS and behavior2013

A preliminary RCT of CBT-AD for adherence and depression among HIV-positive Latinos on the U.S.-Mexico border: the Nuevo Día study.

Jane M Simoni, John S Wiebe, John A Sauceda, David Huh, Giselle Sanchez, Virginia Longoria, C Andres Bedoya, Steven A Safren

2 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AIDS and behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 55 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 12 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03668379 nacompletednot on this mapstarted 2020, after this paper: background citation

An Adaptive Treatment Intervention for Depression and Engagement in HIV Care Among Latinos Living With HIV

TypeinterventionalSponsorUniversity of California, San FranciscoRan2020 to 2022Enrolled10ConditionsDepressionArmsAugment w/mHealth, Maintenance, Switch to CBT & mHealth, Augment w/BAT & mHealth
NCT05734313 narecruitingnot on this mapstarted 2023, after this paper: background citation

Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression in Young Adults With Type 1 Diabetes

TypeinterventionalSponsorAlbert Einstein College of MedicineRan2023 to 2027Enrolled94ConditionsDiabetes, Type 1 DiabetesArmsUnified protocol for cognitive behavioral therapy (UP-CBT), Continuous Glucose Monitoring (CGM)
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 12 syntheses or guidelines pooled it, 97 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jane M SimoniDepartment of Psychology, University of Washington, 3909 W. Stevens Way NE, Campus Box 351525, Seattle, WA, 98195-1525, USA, jsimoni@uw.edu.
John S Wiebe
John A Sauceda
David Huh
Giselle Sanchez
Virginia Longoria
C Andres Bedoya
Steven A Safren
The University of Texas at El Paso · USUniversity of Washington · USHarvard University Press · USMassachusetts General Hospital · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
Addressing Depression and ART Adherence in HIV+ Adults on the US-Mexico BorderR34MH084674 · NIMH · UNIVERSITY OF WASHINGTON · PI SIMONI, JANE M. · 2008 to 2010
$769k
Mentoring Diverse Scientists in Global HIV Research on Mental Health & AdherenceK24MH093243 · NIMH · UNIVERSITY OF WASHINGTON · PI SIMONI, JANE M. · 2011 to 2014
$590k
NIAID NIH HHS P30 AI027757NIMH NIH HHS 1R34MH08674NIMH NIH HHS K24 MH093243NIMH NIH HHS R34 MH084674NIMH NIH HHS R34MH084674-S1
6 · The paper itself

Abstract

We conducted a preliminary RCT among 40 HIV-positive Latinos of Mexican descent on the U.S.-Mexico border who indicated imperfect adherence and depressive symptomatology. Participants were randomly assigned to culturally adapted cognitive-behavioral therapy for adherence and depression with an alarmed pillbox or usual care. Outcomes were depressive symptoms (self-report and blind clinician ratings), adherence (self-report and electronic pillbox), and biological markers. The intervention, delivered in English and Spanish, proved feasible and acceptable. Generalized estimating equations in intent-to-treat analyses showed some effects of "moderate" to "large" size, with maintenance over time. For example, intervention (vs. control) participants demonstrated at post-intervention a greater drop in BDI scores (OR = -3.64, p = 0.05) and greater adherence according to the electronic pillbox (OR = 3.78, p = 0.03). Biological markers indicated some relative improvement for CD4 count but not VL. The promising results suggest a larger trial to determine efficacy is warranted.

Indexed as

Cognitive Behavioral TherapyDrug MonitoringHispanic or LatinoAdultCD4 Lymphocyte CountDepressionFeasibility StudiesFemaleHIV InfectionsHumansMaleMedication AdherenceMexicoMiddle AgedPatient Acceptance of Health CarePatient Compliance

Identifiers

PMID23812892
PMCPMC3788062
OpenAlexW2039579803

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.