Evidence map›Paper›PMID 23812679›Full record

ArticleInternational journal of clinical pharmacy2013

Potentially inappropriate prescribing and drug-drug interactions among elderly Chinese nursing home residents in Macao.

Cheng Kin Lao, Sao Chan Ho, Ka Kit Chan, Chon Fai Tou, Henry Hoi Yee Tong, Alexandre Chan

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In one paragraph

Article in International journal of clinical pharmacy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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  8. Drug-Related Problems and Polypharmacy in Nursing Home Residents: A Cross-Sectional Study.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Cheng Kin LaoSchool of Health Sciences, Macao Polytechnic Institute, Rua de Luís Gonzaga Gomes, Macao, People's Republic of China, cklao@ipm.edu.mo.
Sao Chan Ho
Ka Kit Chan
Chon Fai Tou
Henry Hoi Yee Tong
Alexandre Chan
Macao Polytechnic University · MONational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ageing of the population has become a concern all over the world, including Macao. In general, older people are more prone to adverse drug events which can result from potentially inappropriate medication (PIM) use and drug-drug interactions (DDIs).

objectiveThis study was designed to evaluate the prevalence of PIM use and DDIs among elderly nursing home residents in Macao, and to find out the factors associated with these drug-related problems.

settingThis study was conducted in the largest nursing home in Macao, with a bed capacity of 168.

methodAll data of this cross-sectional study were collected from medical charts and medication administration records. PIM use was determined by the screening tool of older person's prescription (STOPP) criteria and potential DDIs were detected using the preset criteria of two compendia, Drug-Reax and Lexi-Interact. Multivariate logistic regression analysis was performed to identify the independent factors associated with each drug-related problem.

main outcome measuresThe proportions of elderly nursing home residents who regularly used PIMs and who were exposed to DDIs.

resultsA total of 114 elderly residents were eligible for PIM analysis. They consumed an average of 6.9 ± 3.1 different medications. About 46.5 % of them regularly used one or more PIMs. The prevalence of DDIs was 37.8 % among the 111 elderly residents who consumed at least two different medications. An increased number of drugs used was identified as the independent factor associated with PIM use and DDIs (p < 0.05). However, the use of STOPP-related PIMs did not appear to raise the likelihood of DDIs among the study population.

conclusionBoth PIM use and DDIs are common among elderly nursing home residents in Macao. Further studies should be conducted to evaluate the clinical outcomes of pharmacist-led interventions for elderly residents in the local nursing home setting.

Indexed as

AgingDrug InteractionsAgedAged, 80 and overChinaCross-Sectional StudiesDrug MonitoringDrug-Related Side Effects and Adverse ReactionsFemaleGeriatric AssessmentHomes for the AgedHumansIatrogenic DiseaseInappropriate PrescribingMaleNursing Homes

Identifiers

PMID23812679
OpenAlexW2004453556

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.