ReviewViruses2013
Chromatin, non-coding RNAs, and the expression of HIV.
Review in Viruses, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Genetic variation of the HIV-1 subtype C transmitted/founder viruses long terminal repeat elements and the impact on transcription activation potential and clinical disease outcomes.PLoS pathogens · 2023Article
- Arabidopsis HEAT SHOCK TRANSCRIPTION FACTORA1b regulates multiple developmental genes under benign and stress conditions.Journal of experimental botany · 2018Article
- Differentially expressed host long intergenic noncoding RNA and mRNA in HIV-1 and HIV-2 infection.Scientific reports · 2018Article
- Dynamics of the Gene Regulatory Network of HIV-1 and the Role of Viral Non-coding RNAs on Latency Reversion.Frontiers in physiology · 2018Article
- Systemic HIV-1 infection produces a unique glial footprint in humanized mouse brains.Disease models & mechanisms · 2017Article
- Biogenesis and Transcriptional Regulation of Long Noncoding RNAs in the Human Immune System.Journal of immunology (Baltimore, Md. : 1950) · 2016Review
- Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay.Scientific reports · 2016Article
- Gene-expression reversal of lncRNAs and associated mRNAs expression in active vs latent HIV infection.Scientific reports · 2016Article
- Comparative Analysis of Tat-Dependent and Tat-Deficient Natural Lentiviruses.Veterinary sciences · 2015Review
- Bioinformatics and HIV latency.Current HIV/AIDS reports · 2015Review
- Promoter Targeting RNAs: Unexpected Contributors to the Control of HIV-1 Transcription.Molecular therapy. Nucleic acids · 2015Review
- Review
- HIV-1, human interaction database: current status and new features.Nucleic acids research · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
HIV is a chronic viral infection affecting an estimated 34 million people worldwide. Current therapies employ the use of a cocktail of antiretroviral medications to reduce the spread and effects of HIV, however complete eradication from an individual currently remains unattainable. Viral latency and regulation of gene expression is a key consideration when developing effective treatments. While our understanding of these processes remains incomplete new developments suggest that non-coding RNA (ncRNA) mediated regulation may provide an avenue to controlling both viral expression and latency. Here we discuss the importance of known regulatory mechanisms and suggest directions for further study, in particular the use ncRNAs in controlling HIV expression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.