ArticleObstetrics and gynecology2013
A pharmacologic approach to the use of glyburide in pregnancy.
Article in Obstetrics and gynecology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01947699 (Glycemic Profile in Women With Gestational Diabetes Treated With Glyburide), which is not on this map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Glycemic Profile in Women With Gestational Diabetes Treated With Glyburide
Who cites it
17 citing papers in PubMed, 38 citations in OpenAlex.
- Glibenclamide and metfoRmin versus stAndard care in gEstational diabeteS (GRACES): a feasibility open label randomised trial.BMC pregnancy and childbirth · 2017Trial
- Pharmacokinetic Characterization of Labetalol in Pregnancy (The CLIP Study): A Prospective Observational Longitudinal Pharmacokinetic/Pharmacodynamic Cohort Study During Pregnancy and Postpartum.Journal of clinical medicine · 2025Article
- Gestational diabetes mellitus and COVID-19: The epidemic during the pandemic.World journal of diabetes · 2023Review
- Glibenclamide Increases Nitric Oxide Levels and Decreases Oxidative Stress in an In Vitro Model of Preeclampsia.Antioxidants (Basel, Switzerland) · 2022Article
- Changing patterns in medication prescription for gestational diabetes during a time of guideline change in the USA: a cross-sectional study.BJOG : an international journal of obstetrics and gynaecology · 2022 · on this mapArticle
- Gestational Diabetes: Overview with Emphasis on Medical Management.International journal of environmental research and public health · 2020Review
- The Use of Non-insulin Agents in Gestational Diabetes: Clinical Considerations in Tailoring Therapy.Current diabetes reports · 2019Review
- Gestational Diabetes Mellitus.Endocrinology and metabolism clinics of North America · 2019Review
- Pharmacotherapy for gestational diabetes mellitus: still insulin, or what about sulfonylureas?Annals of translational medicine · 2018Article
- A cautionary response to SMFM statement: pharmacological treatment of gestational diabetes.American journal of obstetrics and gynecology · 2018Article
- Oral Agents for the Treatment of Gestational Diabetes.Current diabetes reports · 2018Review
- Research Gaps in Gestational Diabetes Mellitus: Executive Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.Obstetrics and gynecology · 2018Article
- Pregnancy outcomes in women with an early diagnosis of gestational diabetes mellitus.Diabetes research and clinical practice · 2018Article
- Review
- Examining the Starting Dose of Glyburide in Gestational Diabetes.American journal of perinatology · 2016Article
- Basic obstetric pharmacology.Seminars in perinatology · 2014Review
- Gestational diabetes mellitus management with oral hypoglycemic agents.Seminars in perinatology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Despite widespread use of glyburide to treat pregnancy-related hyperglycemia, the dosing regimen is based in large part on pharmacokinetic and pharmacodynamic studies in men and nonpregnant women. Like many medications used by pregnant women, adequate pharmacokinetic and pharmacodynamic data in pregnancy have been sorely lacking. This lack of information can lead to both overdosing with excessive side effects and underdosing with an inadequate therapeutic response. Both of these problems may apply to glyburide use in pregnancy. This commentary provides a pharmacologic basis for altering the glyburide administration regimen. Taking glyburide 1 hour before a meal may improve efficacy in patients with pregnancy-related hyperglycemia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.