ArticleObstetrics and gynecology2013
Tubal factor infertility and perinatal risk after assisted reproductive technology.
Article in Obstetrics and gynecology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Endometriosis increases the risk of gestational diabetes: a meta-analysis stratified by mode of conception, disease localization and severity.Scientific reports · 2023Pooled it
- Preconception Chlamydia trachomatis seropositivity and fecundability, live birth, and adverse pregnancy outcomes.Fertility and sterility · 2025Trial
- Gestational and postpartum maternal consequences of gestational diabetes mellitus.Frontiers in endocrinology · 2026Article
- Non-Sexually Transmitted Infection (STI)-Related Pelvic Inflammatory Disease (PID).Microorganisms · 2025Review
- Factors influencing the birth weight of ART-conceived offspring.Journal of assisted reproduction and genetics · 2025Review
- Evaluation of two luteal support regimens, intramuscular progesterone and progesterone vaginal gel, for vitrified-warmed embryo transfer in women with chronic salpingitis: a single-center 8-year retrospective study.European journal of medical research · 2024Article
- Long-Term Effects of ART on the Health of the Offspring.International journal of molecular sciences · 2023Review
- Association of infertility cause with perinatal outcomes in a freeze-all policy: an analysis including 10,151 singleton newborns.AJOG global reports · 2023Article
- Incidence and risk factors for early pregnancy loss in women with first pregnancy undergoing in vitro fertilization-embryo transfer.BMC pregnancy and childbirth · 2022Article
- Association of adverse birth outcomes with in vitro fertilization after controlling infertility factors based on a singleton live birth cohort.Scientific reports · 2022Article
- Assisted Reproductive Technology Treatment, the Catalyst to Amplify the Effect of Maternal Infertility on Preterm Birth.Frontiers in endocrinology · 2022Article
- The effect of donor and recipient race on outcomes of assisted reproduction.American journal of obstetrics and gynecology · 2021Article
- Comparison of Genome-Wide DNA Methylation Profiles of Human Fetal Tissues Conceived byFrontiers in cell and developmental biology · 2021Article
- Chronic fetal hypoxia disrupts the peri-conceptual environment in next-generation adult female rats.The Journal of physiology · 2019Article
- Genital tract infection and associated factors affect the reproductive outcome in fertile females and females undergoingBiomedical reports · 2019Article
- Evaluating effects of prenatal exposure to phthalate mixtures on birth weight: A comparison of three statistical approaches.Environment international · 2018Article
- Arabian Peninsula ethnicity is associated with lower ovarian reserve and ovarian response in women undergoing fresh ICSI cycles.Journal of assisted reproduction and genetics · 2018Article
- Assisted reproduction and risk of preterm birth in singletons by infertility diagnoses and treatment modalities: a population-based study.Journal of assisted reproduction and genetics · 2017Article
- Population-attributable fraction of tubal factor infertility associated with chlamydia.American journal of obstetrics and gynecology · 2017Article
- Maternal Racial and Ethnic Disparities in Neonatal Birth Outcomes With and Without Assisted Reproduction.Obstetrics and gynecology · 2017Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo assess trends of tubal factor infertility and to evaluate risk of miscarriage and delivery of preterm or low birth weight (LBW) neonates among women with tubal factor infertility using assisted reproductive technology (ART).
methodsWe assessed trends of tubal factor infertility among all fresh and frozen, donor, and nondonor ART cycles performed annually in the United States between 2000 and 2010 (N=1,418,774) using the National ART Surveillance System. The data set was then limited to fresh, nondonor in vitro fertilization cycles resulting in pregnancy to compare perinatal outcomes for cycles associated with tubal compared with male factor infertility. We performed bivariate and multivariable analyses controlling for maternal characteristics and calculated adjusted risk ratios (RRs) and 95% confidence intervals (CI).
resultsThe percentage of ART cycles associated with tubal factor infertility diagnoses decreased from 2000 to 2010 (26.02-14.81%). Compared with male factor infertility, tubal factor portended an increased risk of miscarriage (14.0% compared with 12.7%, adjusted RR 1.08, 95% CI 1.04-1.12); risk was increased for both early and late miscarriage. Singleton neonates born to women with tubal factor infertility had an increased risk of preterm birth (15.8% compared with 11.6%, adjusted RR 1.27, 95% CI 1.20-1.34) and LBW (10.9% compared with 8.5%, adjusted RR 1.28, 95% CI 1.20-1.36). Significant increases in risk persisted for early and late preterm delivery and very low and moderately LBW delivery. A significantly elevated risk was also detected for twin, but not triplet, pregnancies.
conclusionTubal factor infertility, which is decreasing in prevalence in the United States, is associated with an increased risk of miscarriage, preterm birth, and LBW delivery as compared with couples with male factor infertility using ART.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.