ArticleIntensive care medicine2013
Resuscitation of patients with septic shock: please "mind the gap"!
Article in Intensive care medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07179276 (Veno-arterial Carbon Dioxide Partial Pressure Difference), which is not on this map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock: A Multicenter Prospective Randomized Trial (CARBON)
Who cites it
42 citing papers in PubMed.
- What If We Let It Fibrillate? New Perspective on Atrial Fibrillation in Sepsis.Current medical science · 2026Review
- Shunt: pathophysiological mechanisms and clinical implications of ineffective circulating volume.Frontiers in physiology · 2026Review
- Jugular bulb venous to arterial carbon dioxide gradient is associated with treatment-responsive phenotypes of hypoxic-ischemic brain injury.Resuscitation plus · 2025Article
- Use of COAnnals of intensive care · 2025Review
- Regional venous-to-arterial carbon dioxide pressure and content differences during endotoxemic shock: influence of hydrogen ion accumulation vs. Haldane effect.Intensive care medicine experimental · 2025Article
- Lactate and COFrontiers in cardiovascular medicine · 2025Article
- The Evolution of Central Venous-to-arterial Carbon Dioxide Difference (PCOIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Markers of Tissue Perfusion as Predictors of Adverse Outcomes in Patients with Left Ventricular Dysfunction Undergoing Coronary Artery Bypass Surgery.Arquivos brasileiros de cardiologia · 2024Article
- Fluids and Early Vasopressors in the Management of Septic Shock: Do We Have the Right Answers Yet?Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2023Review
- Use of COJournal of cardiovascular development and disease · 2023Review
- Hemodynamic monitoring in cardiogenic shock.Journal of intensive medicine · 2023Review
- Article
- Prognostic Value of PCO2 Gap in Adult Septic Shock Patients: A Systematic Review and Meta-Analysis.Turkish journal of anaesthesiology and reanimation · 2022Article
- PcvCOIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
- The Pathophysiology and Management of Hemorrhagic Shock in the Polytrauma Patient.Journal of clinical medicine · 2021Review
- Pathophysiology and clinical implications of the veno-arterial PCOCritical care (London, England) · 2021Review
- Central venous-to-arterial PCOScientific reports · 2021Article
- Biochemical markers for clinical monitoring of tissue perfusion.Molecular and cellular biochemistry · 2021Review
- Performance of Lactate and COFrontiers in cardiovascular medicine · 2021Article
- The Value of Combining Carbon Dioxide Gap and Oxygen-Derived Variables with Lactate Clearance in Predicting Mortality after Resuscitation of Septic Shock Patients.Critical care research and practice · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.