ArticleEuropean radiology2013
Diagnostic performance of computed tomography coronary angiography to detect and exclude left main and/or three-vessel coronary artery disease.
Article in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sublingual Nitroglycerin Administration in Coronary Computed Tomography Angiography: a Systematic Review.European radiology · 2015Pooled it
- Imaging of Left Main Coronary Artery; Untangling the Gordian Knot.Reviews in cardiovascular medicine · 2023Review
- Nationwide Trends of Gatekeeper to Invasive Coronary Angiography in Suspected Coronary Artery Disease.Korean circulation journal · 2022Article
- The Effects of a Vasodilator on Transluminal Attenuation Gradient at Coronary Computed Tomography Angiography.Korean journal of radiology · 2020Article
- Accuracy of computed tomography for selecting the revascularization method based on SYNTAX score II.European radiology · 2018Article
- Dobutamine stress-induced ischemic right ventricular dysfunction in patients with three-vessel coronary artery disease.Electronic physician · 2018Article
- CT myocardial perfusion imaging: ready for prime time?European radiology · 2018Article
- CT as gatekeeper of invasive coronary angiography in patients with suspected CAD.Cardiovascular diagnosis and therapy · 2017Review
- Single injection protocol for coronary and lower extremity CT angiographies in patients suspected for peripheral arterial disease.Medicine · 2016Observational
- High-risk coronary artery disease, but normal myocardial perfusion: A matter of concern?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Finding the Gatekeeper to the Cardiac Catheterization Laboratory: Coronary CT Angiography or Stress Testing?Journal of the American College of Cardiology · 2015Review
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Authors and funding
10 authors.
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Abstract
objectivesTo determine the diagnostic performance of CT coronary angiography (CTCA) in detecting and excluding left main (LM) and/or three-vessel CAD ("high-risk" CAD) in symptomatic patients and to compare its discriminatory value with the Duke risk score and calcium score. MATERIALS AND
methodsBetween 2004 and 2011, a total of 1,159 symptomatic patients (61 ± 11 years, 31 % women) with stable angina, without prior revascularisation underwent both invasive coronary angiography (ICA) and CTCA. All patients gave written informed consent for the additional CTCA. High-risk CAD was defined as LM and/or three-vessel obstructive CAD (≥50 % diameter stenosis).
resultsA total of 197 (17 %) patients had high-risk CAD as determined by ICA. The sensitivity, specificity, positive predictive value, negative predictive value, positive and negative likelihood ratios of CTCA were 95 % (95 % CI 91-97 %), 83 % (80-85 %), 53 % (48-58 %), 99 % (98-99 %), 5.47 and 0.06, respectively. CTCA provided incremental value (AUC 0.90, P < 0.001) in the discrimination of high-risk CAD compared with the Duke risk score and calcium score.
conclusionsCTCA accurately excludes high-risk CAD in symptomatic patients. The detection of high-risk CAD is suboptimal owing to the high percentage (47 %) of overestimation of high-risk CAD. CTCA provides incremental value in the discrimination of high-risk CAD compared with the Duke risk score and calcium score. KEY POINTS: • Computed tomography coronary angiography (CTCA) accurately excludes high-risk coronary artery disease. • CTCA overestimates high-risk coronary artery disease in 47 %. • CTCA discriminates high-risk CAD better than clinical evaluation and coronary calcification.
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