ArticleWorld journal of surgery2013
Risk factors of hospital mortality after re-laparotomy for post-hepatectomy hemorrhage.
Article in World journal of surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 19 citations in OpenAlex.
- Elegans-Inspired Magnetic Polyurethane Soft Robot (MPSR) for Closed Visceral Secondary Hemostasis In Situ.Advanced healthcare materials · 2026Article
- Prevalence of re-laparotomy and its risk factors in patients who underwent gastrointestinal procedure at Referral Hospital in Ethiopia.PloS one · 2026Article
- Preoperative Risk Factors for 30-Day Reoperation in Patients Undergoing Hepatic Resections for Malignancy.Indian journal of surgical oncology · 2017Article
- Laparoscopic hepatectomy by curettage and aspiration: a report of 855 cases.Surgical endoscopy · 2016Article
- Reoperation for post-hepatectomy hemorrhage: increased risk of mortality.Langenbeck's archives of surgery · 2014Article
- Management of post-hepatectomy complications.World journal of gastroenterology · 2013Review
- Endoscopic management of biliary leakage after hepatectomy and analysis of its influencing factors.Therapeutic advances in gastrointestinal endoscopyArticle
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPost-hepatectomy hemorrhage (PHH) requiring re-laparotomy is a life-threatening situation and is associated with a considerably high hospital mortality rate. However, risk factors of hospital mortality in patients with this condition have not yet been investigated.
methodsThe perioperative data of 258 patients with hepatocellular carcinoma who underwent re-laparotomy for PHH from 1997 to 2011 were retrospectively reviewed and evaluated by univariate and multivariate analyses to identify risk factors of hospital mortality.
resultHospital death occurred in 43 patients between 16 h and 40 days after re-laparotomy, and the overall mortality rate was 16.7 %. The median time lag between first recognition of active bleeding and re-laparotomy was 6 h (range 0.5-34 h). The mortality of patients undergoing late re-laparotomy (≥6 h) was much higher than those undergoing early re-laparotomy (<6 h) (25 vs 8.6 %; P = 0.001). Multivariate analysis showed early time period (1997-2004) (P = 0.040), liver cirrhosis (P = 0.025), ineffective hemostasis during re-laparotomy due to coagulopathy (P = 0.038), late re-laparotomy (≥6 h) (P = 0.032), postoperative liver failure (P = 0.001), and postoperative acute renal failure requiring hemodialysis (P = 0.024) were independent risk factors of hospital mortality.
conclusionImmediate re-laparotomy is a key factor to reduce hospital mortality for patients with active bleeding after partial hepatectomy. More care should be taken in those patients who develop acute liver failure and/or serious acute renal failure after re-laparotomy.
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