Evidence map›Paper›PMID 23811281›Full record

ReviewAntiviral research2013

Chikungunya fever: epidemiology, clinical syndrome, pathogenesis and therapy.

Simon-Djamel Thiberville, Nanikaly Moyen, Laurence Dupuis-Maguiraga, Antoine Nougairede, Ernest A Gould, Pierre Roques, Xavier de Lamballerie

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Antiviral research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 251 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
251citing papers in PubMed, 11 pooled it
37.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

251 citing papers in PubMed, 11 syntheses or guidelines pooled it, 525 citations in OpenAlex.

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  9. Prevalence of chronic comorbidities in chikungunya: A systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2018
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  12. Trial
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  15. Assessing the Vector Competence for Chikungunya Virus in Mosquitoes.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
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  17. Review
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191 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Simon-Djamel ThibervilleUMR_D 190 "Emergence des Pathologies Virales" (Aix-Marseille Univ. IRD French Institute of Research for Development EHESP French School of Public Health), Marseille, France; University Hospital Institute for Infectious Disease and Tropical Medicine, Marseille, France. Electronic address: djamt@yahoo.fr.
Nanikaly Moyen
Laurence Dupuis-Maguiraga
Antoine Nougairede
Ernest A Gould
Pierre Roques
Xavier de Lamballerie
École des Hautes Études en Santé Publique · FRAix-Marseille Université · FRInfectious Disease Models and Innovative Therapies · FRInstitut de Recherche pour le Développement · FRUniversité Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chikungunya virus (CHIKV) is the aetiological agent of the mosquito-borne disease chikungunya fever, a debilitating arthritic disease that, during the past 7years, has caused immeasurable morbidity and some mortality in humans, including newborn babies, following its emergence and dispersal out of Africa to the Indian Ocean islands and Asia. Since the first reports of its existence in Africa in the 1950s, more than 1500 scientific publications on the different aspects of the disease and its causative agent have been produced. Analysis of these publications shows that, following a number of studies in the 1960s and 1970s, and in the absence of autochthonous cases in developed countries, the interest of the scientific community remained low. However, in 2005 chikungunya fever unexpectedly re-emerged in the form of devastating epidemics in and around the Indian Ocean. These outbreaks were associated with mutations in the viral genome that facilitated the replication of the virus in Aedes albopictus mosquitoes. Since then, nearly 1000 publications on chikungunya fever have been referenced in the PubMed database. This article provides a comprehensive review of chikungunya fever and CHIKV, including clinical data, epidemiological reports, therapeutic aspects and data relating to animal models for in vivo laboratory studies. It includes Supplementary Tables of all WHO outbreak bulletins, ProMED Mail alerts, viral sequences available on GenBank, and PubMed reports of clinical cases and seroprevalence studies.

Indexed as

Alphavirus InfectionsAnimalsAntiviral AgentsChikungunya FeverChikungunya virusHumansPhylogenyAntiviral AgentsAlphavirusAntiviral therapyArbovirusChikungunya feverChikungunya virus

Identifiers

PMID23811281
PMCPMC7114207
OpenAlexW1963749198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.