Evidence map›Paper›PMID 23811222›Full record

ArticleScience (New York, N.Y.)2013

Identification of wheat gene Sr35 that confers resistance to Ug99 stem rust race group.

Cyrille Saintenac, Wenjun Zhang, Andres Salcedo, Matthew N Rouse, Harold N Trick, Eduard Akhunov, Jorge Dubcovsky

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 153 papers.

0numbers the graph read from it
0cells of the map it votes in
153citing papers in PubMed
38.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

153 citing papers in PubMed, 311 citations in OpenAlex.

  1. Mechanisms and balanced regulation of plant immunity.Nature reviews. Molecular cell biology · 2026
    Review
  2. Article
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  5. Harnessing primary, secondary and tertiary genepools for durable wheat disease resistance.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Progress and innovations of gene cloning in wheat and its close relatives.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Genome-wide atlas of rust resistance loci in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. High-resolution mapping of Ryd4TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024
    Article
  19. Article
  20. An online database for einkorn wheat to aid in gene discovery and functional genomics studies.Database : the journal of biological databases and curation · 2023
    Article

93 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Cyrille Saintenac *Kansas State University, Dept. Plant Pathology, Manhattan, KS 66506.
Wenjun Zhang *University of California, Davis Dept. Plant Sciences, Davis, CA 95616.
Andres SalcedoKansas State University, Dept. Plant Pathology, Manhattan, KS 66506.
Matthew N RouseUSDA-ARS Cereal Disease Laboratory, St. Paul, MN 55108.
Harold N TrickKansas State University, Dept. Plant Pathology, Manhattan, KS 66506.
Eduard Akhunov *Kansas State University, Dept. Plant Pathology, Manhattan, KS 66506.
Jorge Dubcovsky *University of California, Davis Dept. Plant Sciences, Davis, CA 95616.
Kansas State University · USHoward Hughes Medical Institute · USUniversity of California, Davis · US

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Wheat stem rust, caused by Puccinia graminis f. sp. tritici (Pgt), is a devastating disease that can cause severe yield losses. A previously uncharacterized Pgt race, designated Ug99, has overcome most of the widely used resistance genes and is threatening major wheat production areas. Here, we demonstrate that the Sr35 gene from Triticum monococcum is a coiled-coil, nucleotide-binding, leucine-rich repeat gene that confers near immunity to Ug99 and related races. This gene is absent in the A-genome diploid donor and in polyploid wheat but is effective when transferred from T. monococcum to polyploid wheat. The cloning of Sr35 opens the door to the use of biotechnological approaches to control this devastating disease and to analyses of the molecular interactions that define the wheat-rust pathosystem.

Indexed as

BasidiomycotaGenes, PlantAlternative SplicingAmino Acid SequenceCloning, MolecularDisease ResistanceHaplotypesMolecular Sequence AnnotationMolecular Sequence DataMutationPhylogenyPlant DiseasesPlant ProteinsPlants, Genetically ModifiedPlant StemsPolymorphism, Single NucleotidePlant Proteins

Identifiers

PMID23811222
PMCPMC4748951
OpenAlexW1986610242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.