ArticleImmunity2013
K⁺ drops tilt the NLRP3 inflammasome.
Article in Immunity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of post-translational modifications and subcellular localization on NLRP3 inflammasome activation: A systematic review.Cell communication and signaling : CCS · 2025Pooled it
- Two-pore potassium channel TREK-1 (K2P2.1) regulates NLRP3 inflammasome activity in macrophages.American journal of physiology. Lung cellular and molecular physiology · 2024Article
- Role of NLRP3 inflammasome-mediated neuronal pyroptosis and neuroinflammation in neurodegenerative diseases.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023Review
- Can pyroptosis be a new target in rheumatoid arthritis treatment?Frontiers in immunology · 2023Review
- The Role of Peroxiredoxins in the Regulation of Sepsis.Antioxidants (Basel, Switzerland) · 2022Review
- Mechanism of Gene-Environment Interactions Driving Glial Activation in Parkinson's Diseases.Current environmental health reports · 2021Review
- Article
- Caspase-11 Non-canonical Inflammasomes in the Lung.Frontiers in immunology · 2020Review
- Review
- DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome.Nature · 2019Article
- Guanylate-binding proteins at the crossroad of noncanonical inflammasome activation during bacterial infections.Journal of leukocyte biology · 2019Review
- ABRO1 promotes NLRP3 inflammasome activation through regulation of NLRP3 deubiquitination.The EMBO journal · 2019Article
- Treponema pallidum promotes macrophage polarization and activates the NLRP3 inflammasome pathway to induce interleukin-1β production.BMC immunology · 2018Article
- An update on cell intrinsic negative regulators of the NLRP3 inflammasome.Journal of leukocyte biology · 2018Review
- Neurodegeneration and NLRP3 inflammasome expression in the anterior thalamus of SOD1(G93A) ALS mice.Brain pathology (Zurich, Switzerland) · 2018Article
- UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis.The Journal of clinical investigation · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Unwarranted NLRP3 activation causes inflammatory disease. Its activation must therefore be specifically licensed. In this issue of Immunity, Munoz-Planillo et al. (2013) reveal K⁺ efflux as the sole common denominator of an array of unrelated stimuli engaging this inflammasome.
Indexed as
Identifiers
23809157What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.