ArticleEuropean radiology2013
Detection of coronary artery stenosis with sub-milliSievert radiation dose by prospectively ECG-triggered high-pitch spiral CT angiography and iterative reconstruction.
Article in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 65 citations in OpenAlex.
- High-pitch coronary CT angiography at 70 kVp with low contrast medium volume: comparison of 80 and 100 kVp high-pitch protocols.Medicine · 2014Trial
- Radiation Dose and Image Quality of a High-Pitch Prospective Spiral First Approach in Coronary Computed Tomography Angiography (CCTA).Journal of cardiovascular development and disease · 2021Article
- Diagnostic performance of deep learning-based vascular extraction and stenosis detection technique for coronary artery disease.The British journal of radiology · 2020Article
- Image quality and diagnostic accuracy of coronary CT angiography derived from low-dose dynamic CT myocardial perfusion: a feasibility study with comparison to invasive coronary angiography.European radiology · 2019Article
- Radiation dose of coronary CT angiography with a third-generation dual-source CT in a "real-world" patient population.European radiology · 2019Article
- Coronary artery calcium scoring with photon-counting CT: first in vivo human experience.The international journal of cardiovascular imaging · 2019Article
- Low-Dose Radiation Advances in Coronary Computed Tomography Angiography in the Diagnosis of Coronary Artery Disease.Current cardiology reviews · 2019Review
- Coronary computed tomography angiography in the evaluation of intermediate risk asymptomatic individuals.La Radiologia medica · 2018Article
- Pregnancy-Associated Myocardial Infarction.Current treatment options in cardiovascular medicine · 2018Review
- The role of advanced reconstruction algorithms in cardiac CT.Cardiovascular diagnosis and therapy · 2017Review
- Optimizing radiation dose by using advanced modelled iterative reconstruction in high-pitch coronary CT angiography.European radiology · 2016Article
- Computed Tomography Angiography with a 192-slice Dual-source Computed Tomography System: Improvements in Image Quality and Radiation Dose.Journal of clinical imaging science · 2016Article
- The Essentials of Cardiac Computerized Tomography.Cardiology and therapy · 2015Article
- Dose levels and image quality of second-generation 128-slice dual-source coronary CT angiography in clinical routine.La Radiologia medica · 2015Article
- Dual-energy computed tomography for detection of coronary artery disease.Expert review of cardiovascular therapy · 2015Review
- Dual-source cardiac computed tomography angiography (CCTA) in the follow-up of cardiac transplant: comparison of image quality and radiation dose using three different imaging protocols.European radiology · 2015Article
- New Applications of Cardiac Computed Tomography: Dual-Energy, Spectral, and Molecular CT Imaging.JACC. Cardiovascular imaging · 2015Review
- Coronary CT angiography in managing atherosclerosis.International journal of molecular sciences · 2015Review
- High-pitch coronary CT angiography with third generation dual-source CT: limits of heart rate.The international journal of cardiovascular imaging · 2014Article
- Feasibility of prospectively ECG-triggered high-pitch coronary CT angiography with 30 mL iodinated contrast agent at 70 kVp: initial experience.European radiology · 2014Article
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the diagnostic accuracy of sub-milliSievert (mSv) coronary CT angiography (cCTA) using prospectively ECG-triggered high-pitch spiral CT acquisition combined with iterative image reconstruction.
methodsForty consecutive patients (52.9 ± 8.7 years; 30 men) underwent dual-source cCTA using prospectively ECG-triggered high-pitch spiral acquisition. The tube current-time product was set to 50 % of standard-of-care CT examinations. Images were reconstructed with sinogram-affirmed iterative reconstruction. Image quality was scored and diagnostic performance for detection of ≥50 % stenosis was determined with catheter coronary angiography (CCA) as the reference standard.
resultsCT was successfully performed in all 40 patients. Of the 601 assessable coronary segments, 543 (90.3 %) had diagnostic image quality. Per-patient sensitivity for detection of ≥50 % stenosis was 95.7 % [95 % confidence interval (CI), 76.0-99.8 %] and specificity was 94.1 % (95 % CI, 69.2-99.7 %). Per-vessel sensitivity was 89.5 % (95 % CI, 77.8-95.6 %) with 93.2 % specificity (95 % CI, 86.0-97.0 %). The area under the receiver-operating characteristic curve on per-patient and per-vessel levels was 0.949 and 0.913. Mean effective dose was 0.58 ± 0.17 mSv. Mean size-specific dose estimate was 3.14 ± 1.15 mGy.
conclusionsHigh-pitch prospectively ECG-triggered cCTA combined with iterative image reconstruction provides high diagnostic accuracy with a radiation dose below 1 mSv for detection of coronary artery stenosis. KEY POINTS: • Cardiac CT with sub-milliSievert radiation dose is feasible in many patients • High-pitch spiral CT acquisition with iterative reconstruction detects coronary stenosis accurately. • Iterative reconstruction increases who can benefit from low-radiation cardiac CT.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.