ReviewMarine drugs2013
Interpreting the possible ecological role(s) of cyanotoxins: compounds for competitive advantage and/or physiological aide?
Review in Marine drugs, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Can correlational analyses help determine the drivers of microcystin occurrence in freshwater ecosystems? A meta-analysis of microcystin and associated water quality parameters.Environmental monitoring and assessment · 2022Pooled it
- Nutrient disturbance in a shallow aquaculture pond impacts Microcystis gene expression but does not impact bacterial community function during bloom conditions.Journal of phycology · 2026Article
- Occurrence and Diversity of Cyanotoxins and Retinoid Compounds in Antarctic Microbial Mats: Evidence From James Ross Island.Environmental microbiology reports · 2026Article
- Statewide Intensification of Harmful Algal Blooms Across California Lakes and Reservoirs.GeoHealth · 2026Article
- Multi-scale ecological drivers shape the genome flexibility of soil-dwellingISME communications · 2026Article
- Nutrient-driven regulation of saxitoxin gene expression and toxin production in Raphidiopsis raciborskii (Cyanobacteria).Journal of phycology · 2025Article
- Mechanistic prediction of community composition across resource conditions and species richness.Nature communications · 2025Article
- Rapidly increasing cyanobacteria blooms in the subarctic Great Slave Lake: observations from Indigenous, local, and scientific knowledge.Scientific reports · 2025Article
- Growth and anatoxin-a production of Microcoleus (Cyanobacteria) strains from streams in California, USA.Harmful algae · 2025Article
- Health and Environmental Impacts of Cyanobacteria and Cyanotoxins from Freshwater to Seawater.Toxins · 2025Review
- A green microbe for a sustainable future: the versatile applications ofSustainable microbiology · 2025Review
- Emerging contaminants: A One Health perspective.Innovation (Cambridge (Mass.)) · 2024Review
- Nanostructured Magnetic Particles for Removing Cyanotoxins: Assessing Effectiveness and Toxicity In Vitro.Toxins · 2024Article
- Toward a Predictive Understanding of Cyanobacterial Harmful Algal Blooms through AI Integration of Physical, Chemical, and Biological Data.ACS ES&T water · 2024Review
- Microbiome analysis revealsApplied and environmental microbiology · 2024Article
- Allelopathic Potential of the Cyanotoxins Microcystin-LR and Cylindrospermopsin on Green Algae.Plants (Basel, Switzerland) · 2023Article
- Article
- Unraveling the intestinal epithelial barrier in cyanotoxin microcystin-treated Caco-2 cell monolayers.Annals of the New York Academy of Sciences · 2022Article
- Reporting of Freshwater Cyanobacterial Poisoning in Terrestrial Wildlife: A Systematic Map.Animals : an open access journal from MDPI · 2022Review
- Phytoplankton Toxins and Their Potential Therapeutic Applications: A Journey toward the Quest for Potent Pharmaceuticals.Marine drugs · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To date, most research on freshwater cyanotoxin(s) has focused on understanding the dynamics of toxin production and decomposition, as well as evaluating the environmental conditions that trigger toxin production, all with the objective of informing management strategies and options for risk reduction. Comparatively few research studies have considered how this information can be used to understand the broader ecological role of cyanotoxin(s), and the possible applications of this knowledge to the management of toxic blooms. This paper explores the ecological, toxicological, and genetic evidence for cyanotoxin production in natural environments. The possible evolutionary advantages of toxin production are grouped into two main themes: That of "competitive advantage" or "physiological aide". The first grouping illustrates how compounds produced by cyanobacteria may have originated from the need for a cellular defence mechanism, in response to grazing pressure and/or resource competition. The second grouping considers the contribution that secondary metabolites make to improved cellular physiology, through benefits to homeostasis, photosynthetic efficiencies, and accelerated growth rates. The discussion also includes other factors in the debate about possible evolutionary roles for toxins, such as different modes of exposures and effects on non-target (i.e., non-competitive) species. The paper demonstrates that complex and multiple factors are at play in driving evolutionary processes in aquatic environments. This information may provide a fresh perspective on managing toxic blooms, including the need to use a "systems approach" to understand how physico-chemical conditions, as well biological stressors, interact to trigger toxin production.
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