Evidence map›Paper›PMID 23807122›Full record

Trial reportWorld journal of surgery2013

Initial experiences of an enhanced recovery protocol in esophageal surgery.

Rachel L G M Blom, Mark van Heijl, Willem A Bemelman, Markus W Hollmann, Jean H G Klinkenbijl, Olivier R C Busch, Mark I van Berge Henegouwen

Registry-linked trialAbstract readClinical TrialComparative Study
PubMed Publisher
In one paragraph

Trial report in World journal of surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02478996 (Internet-based Perioperative Exercise Program in Patients With Barrett's Carcinoma Scheduled for Esophagectomy), which is not on this map. Cited by 31 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 7 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02478996 naunknown statusnot on this mapstarted 2015, after this paper: background citation

Internet-based Perioperative Exercise Program in Patients With Barrett's Carcinoma Scheduled for Esophagectomy (iPEP Study) A Prospective Randomized-controlled Pilot Trial

TypeinterventionalSponsorUniversity of LeipzigRan2015 to 2019Enrolled80ConditionsBarrett EsophagusArmsInternet-based exercise program
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 7 syntheses or guidelines pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Impact of enhanced recovery program on patients with esophageal cancer in comparison with traditional care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Pooled it
  6. Pooled it
  7. Systematic review of enhanced recovery after gastro-oesophageal cancer surgery.Annals of the Royal College of Surgeons of England · 2015
    Pooled it
  8. Trial
  9. Review
  10. Laparoscopic round‑ligament duodenostomy synchronized with posterior mediastinal reconstruction.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Improved anastomotic leakage rates after the "flap and wrap" reconstruction in Ivor Lewis esophagectomy for cancer.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2022
    Observational
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Rachel L G M BlomDepartment of Surgery G4-115, Academic Medical Center, Meibergdreef 9, 1100 DD Amsterdam, The Netherlands. r.l.blom@amc.uva.nl
Mark van Heijl
Willem A Bemelman
Markus W Hollmann
Jean H G Klinkenbijl
Olivier R C Busch
Mark I van Berge Henegouwen
Academic Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA recent development in gastrointestinal surgery is the implementation of enhanced recovery after surgery (ERAS) programs. Evidence regarding the benefit of these programs in patients undergoing esophageal surgery is scarce. We investigated the feasibility and possible benefit of a perioperative ERAS program in patients undergoing esophagectomy for malignant disease.

methodsThe ERAS program was initiated in 2009. Patients who underwent esophagectomy and were treated according to the ERAS program were included. Items of ERAS included preoperative nutrition, early extubation, early removal of nasogastric tube, and early mobilization. Primary outcome parameters were hospital stay and the incidence of postoperative complications. Outcome parameters in the ERAS cohort were compared to a cohort of patients who underwent surgical resection in the year prior to the implementation of the ERAS protocol. A feasibility analysis was performed among a sample of ERAS patients to determine the number of achieved items per patient.

resultsBetween 2008 and August 2010, 181 patients in our department underwent esophagectomy. Of these, 103 patients were included in the ERAS program (ERAS+ group) and were compared to 78 patients who had undergone an esophagectomy in 2008 (ERAS- group). Overall hospital stay was 14 days versus 15 days (ERAS+ and ERAS-, respectively; p = 0.013). There were no significant differences in the incidence of postoperative complications in either group. The percentage of achieved items varied between 42 and 93 % per item.

conclusionsThe implementation of an ERAS program in esophageal surgery was feasible and resulted in a small but significant reduction in overall hospital stay, whereas overall morbidity was not affected.

Indexed as

EsophagectomyRecovery of FunctionAdenocarcinomaAgedCarcinoma, Squamous CellClinical ProtocolsEsophageal NeoplasmsFeasibility StudiesFemaleHumansIncidenceLength of StayMaleMiddle AgedPerioperative CarePostoperative Complications

Identifiers

PMID23807122
OpenAlexW2061158733

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.