Evidence map›Paper›PMID 23806030›Full record

ArticleThe Journal of organic chemistry2013

Synthesis of 2'-deoxy-9-deaza nucleosides using Heck methodology.

Kartik Temburnikar, Kelin Brace, Katherine L Seley-Radtke

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kartik TemburnikarUniversity of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland 21250, United States.
Kelin Brace
Katherine L Seley-Radtke

Funding

Fused Pyrimidine (IsoA) Nucleosides:Design and SynthesisR01CA097634 · NCI · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI RADTKE, KATHERINE L. · 2002 to 2006
$1.5M
Unnatural Base Pairs as DNA BioprobesR01GM073645 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SELEY-RADTKE, KATHERINE L · 2005 to 2009
$1.1M
NCI NIH HHS R01 CA097634NIGMS NIH HHS R01 GM073645
6 · The paper itself

Abstract

During the synthesis of a series of 2'-deoxy-9-deaza nucleosides using Heck methodology, the necessity for a pyrrole protecting group was discovered. The results of this brief study revealed that the benzyloxymethyl (BOM) group proved optimal, and Heck coupling using Jeffery conditions increased the coupling yield significantly. The results are reported herein.

Indexed as

DeoxyguanosineDeoxyribonucleosidesMolecular Conformation2'-deoxy-9-deazaguanosineDeoxyguanosineDeoxyribonucleosides

Identifiers

PMID23806030
PMCPMC5638437

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.