ArticleJournal of interventional gastroenterology2012
Magnetic endoscope imaging (ScopeGuide) elucidates the mechanism of action of the pain-alleviating impact of water exchange colonoscopy - attenuation of loop formation.
Article in Journal of interventional gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Efficacy of Water & Indigo Carmine vs Water or Air Method
Abdominal Compression Administered Early by the Colonoscopist Shortened Insertion Time of Water Exchange Colonoscopy
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Is water exchange superior to water immersion for colonoscopy? A systematic review and meta-analysis.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationPooled it
- Assessing water-assisted colonoscopy in beginner endoscopists: a randomised controlled trial.BMJ open gastroenterology · 2025Trial
- Comparing right colon adenoma detection rate during water exchange and air insufflation: a double-blind randomized controlled trial.Techniques in coloproctology · 2022Trial
- A prospective RCT comparing combined chromoendoscopy with water exchange (CWE) vs water exchange (WE) vs air insufflation (AI) in adenoma detection in screening colonoscopy.United European gastroenterology journal · 2019Trial
- Accuracy of preoperative tumor localization in large bowel using 3D magnetic endoscopic imaging: randomized clinical trial.Surgical endoscopy · 2017Trial
- Water Exchange Method Significantly Improves Adenoma Detection Rate: A Multicenter, Randomized Controlled Trial.The American journal of gastroenterology · 2017Trial
- Flexible IMU Sensor Array For 3D Colonoscope Shape Reconstruction and AI-Based Loop Detection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Unsedated or On-Demand Minimally Sedated Water-Aided Outpatient Colonoscopy in Colorectal Cancer Screening and Surveillance: A Step Forward or Backward? Experience from Daily Practice in a Regional (Nonacademic) Hospital.Diagnostics (Basel, Switzerland) · 2024Article
- JAG consensus statements for training and certification in colonoscopy.Frontline gastroenterology · 2023Article
- Diagnostic ileocolonoscopy: getting the basics right.Frontline gastroenterology · 2020Article
- The advantages of water immersion colonoscopy in ambulatory service.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019Observational
- Systematic review of safety and efficacy of therapeutic endoscopic-retrograde-cholangiopancreatography during pregnancy including studies of radiation-free therapeutic endoscopic-retrograde-cholangiopancreatography.World journal of gastrointestinal endoscopy · 2018Article
- Difference in real-time magnetic image analysis of colonic looping patterns between males and females undergoing diagnostic colonoscopy.Endoscopy international open · 2018Article
- Difficult colonoscopy: air, carbon dioxide, or water insufflation?Intestinal research · 2018Article
- Cecal intubation rates in different eras of endoscopic technological development.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2018Article
- Water-Assisted Colonoscopy.Current treatment options in gastroenterology · 2017Review
- Accuracy of polyp localization at colonoscopy.Endoscopy international open · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe explanation why water exchange colonoscopy produces a significant reduction of pain during colonoscopy is unknown. A recent editorial recommended use of magnetic endoscope imaging (MEI) to elucidate the explanation.
objectiveIn unselected patients to show that MEI documents less frequent loop formation when water exchange is used.
designObservational, performance improvement.
settingVeterans Affairs outpatient endoscopy. PATIENTS: Routine colonoscopy cases.
interventionsColonoscopy using air or water exchange method was performed as previously described. The MEI equipment (ScopeGuide, Olympus) with built-in magnetic sensors displays the configuration of the colonoscope inside the patient. During sedated colonoscopy the endoscopist was blinded to the ScopeGuide images which were recorded and subsequently reviewed.
main outcome measuresLoop formation based on a visual guide provided by Olympus.
resultsThere were 41 and 32 cases in the water exchange and air group, respectively. The sigmoid N loop was most common, followed by the sigmoid alpha loop, and exaggeration of scope curvature at the splenic flexure/transverse colon. Of these, 20/32 vs. 9/41 patients (p=0.0007) had sigmoid looping, and 17/32 vs. 9/41 patients (p=0.0007) had sigmoid/splenic looping when the scope tip was in the transverse colon, in the air and water exchange group, respectively. LIMITATIONS: Colonoscopy method was not blinded and non randomized.
conclusionMEI data objectively demonstrated significantly fewer loops during water exchange colonoscopy, elucidating its mechanism of pain alleviation - attenuation of loop formation. Since MEI feedback enhances cecal intubation by trainees, the role of MEI combined water exchange in speeding up trainee learning curves deserves further evaluations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.