ArticlePloS one2013
In Planta Biocontrol of Pectobacterium atrosepticum by Rhodococcus erythropolis Involves Silencing of Pathogen Communication by the Rhodococcal Gamma-Lactone Catabolic Pathway.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 61 citations in OpenAlex.
- Diverse rhizospheric Bacillus are required for protection against a leaf pathogen.The ISME journal · 2026Article
- Characterization of a quorum-sensing communication based on gamma-butyrolactones inFrontiers in microbiology · 2026Article
- Plant growth-promoting endophytic microbiota from garlic bulbs.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Quorum sensing-related activities of beneficial and pathogenic bacteria have important implications for plant and human health.FEMS microbiology ecology · 2024Review
- Biotechnological Key Genes of theMicroorganisms · 2023Article
- Diversity and characteristics of plant immunity-activating bacteria from Brassicaceae plants.BMC microbiology · 2023Article
- The Role of Quorum Sensing Molecules in Bacterial-Plant Interactions.Metabolites · 2023Review
- Unusual enantiomeric D,L-N-acyl homoserine lactones in Pectobacterium atrosepticum and Pseudomonas aeruginosa.PloS one · 2023Article
- Vineyard practices reduce the incidence ofFrontiers in microbiology · 2023Article
- Synthetic microbial consortia derived from rhizosphere soil protect wheat against a soilborne fungal pathogen.Frontiers in microbiology · 2022Article
- Protective role of the Arabidopsis leaf microbiota against a bacterial pathogen.Nature microbiology · 2021Article
- Importance ofPathogens (Basel, Switzerland) · 2021Article
- Biocontrol of Biofilm Formation: Jamming of Sessile-Associated Rhizobial Communication by Rhodococcal Quorum-Quenching.International journal of molecular sciences · 2021Article
- Biosensors Used for Epifluorescence and Confocal Laser Scanning Microscopies to StudyMicroorganisms · 2021Review
- Review
- Genome-Based Characterization of Plant-AssociatedFrontiers in microbiology · 2021Article
- Searching for New Beneficial Bacterial Isolates of Wild Raspberries for Biocontrol of Phytopathogens-Antagonistic Properties and Functional Characterization.International journal of molecular sciences · 2020Article
- Fighting plant pathogens with cold-active microorganisms: biopesticide development and agriculture intensification in cold climates.Applied microbiology and biotechnology · 2020Review
- Plant growth-promoting activity and quorum quenching-mediated biocontrol of bacterial phytopathogens by Pseudomonas segetis strain P6.Scientific reports · 2020Article
- Potential of a Quorum Quenching Bacteria IsolateFrontiers in microbiology · 2020Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The virulence of numerous Gram-negative bacteria is under the control of a quorum sensing process based on synthesis and perception of N-acyl homoserine lactones. Rhodococcus erythropolis, a Gram-positive bacterium, has recently been proposed as a biocontrol agent for plant protection against soft-rot bacteria, including Pectobacterium. Here, we show that the γ-lactone catabolic pathway of R. erythropolis disrupts Pectobacterium communication and prevents plant soft-rot. We report the first characterization and demonstration of N-acyl homoserine lactone quenching in planta. In particular, we describe the transcription of the R. erythropolis lactonase gene, encoding the key enzyme of this pathway, and the subsequent lactone breakdown. The role of this catabolic pathway in biocontrol activity was confirmed by deletion of the lactonase gene from R. erythropolis and also its heterologous expression in Escherichia coli. The γ-lactone catabolic pathway is induced by pathogen communication rather than by pathogen invasion. This is thus a novel and unusual biocontrol pathway, differing from those previously described as protecting plants from phytopathogens. These findings also suggest the existence of an additional pathway contributing to plant protection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.