ArticleProceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine2013
Changes in dynamic medial tibiofemoral contact mechanics and kinematics after injury of the anterior cruciate ligament: a cadaveric model.
Article in Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 39 citations in OpenAlex.
- Meniscal Dominant Loaders During Simulated Gait: A Cadaveric Study in Human Knees.Orthopaedic journal of sports medicine · 2026Article
- Individual and Combined Effects of Anterior Cruciate Ligament and Lateral Meniscus Injuries and Surgical Interventions on Tibiofemoral Peak Pressure Magnitude Vary by Flexion Angle.Arthroscopy, sports medicine, and rehabilitation · 2025Article
- Preoperative factors associated with failure to reach the patient acceptable symptom state after anterior cruciate ligament reconstruction in patients aged 40 and older.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Delayed ACL reconstruction increases rates of concomitant procedures and risk of subsequent surgery.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Importance of posterior tibial slope in joint kinematics with an anterior cruciate ligament-deficient knee.Bone & joint research · 2022Article
- Stress on the posteromedial region of the proximal tibia increased over time after anterior cruciate ligament injury.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Article
- Synthetic PVA Osteochondral Implants for the Knee Joint: Mechanical Characteristics During Simulated Gait.The American journal of sports medicine · 2021Article
- Radial Tears of the Lateral Meniscus-Two Novel Repair Techniques: A Biomechanical Study.Orthopaedic journal of sports medicine · 2018Article
- Chinese Ethnicity Is Associated With Concomitant Cartilage Injuries in Anterior Cruciate Ligament Tears.Orthopaedic journal of sports medicine · 2018Article
- Loss of ACL function leads to alterations in tibial plateau common dynamic contact stress profiles.Journal of biomechanics · 2017Article
- Kinematics of meniscal- and ACL-transected mouse knees during controlled tibial compressive loading captured using roentgen stereophotogrammetry.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2017Article
- Novel measure of articular instability based on contact stress confirms that the anterior cruciate ligament is a critical stabilizer of the lateral compartment.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2016Article
- In vivo cartilage strain increases following medial meniscal tear and correlates with synovial fluid matrix metalloproteinase activity.Journal of biomechanics · 2015Article
- A statistically-augmented computational platform for evaluating meniscal function.Journal of biomechanics · 2015Article
- Effect of axial loading during knee flexion on ACL end-to-end distance in healthy and ACL-deficient knees.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2015Article
- In vivo measurement of localized tibiofemoral cartilage strains in response to dynamic activity.The American journal of sports medicine · 2015Article
- Image based weighted center of proximity versus directly measured knee contact location during simulated gait.Journal of biomechanics · 2014Article
- Length of anterior cruciate ligament affects knee kinematics and kinetics using a musculoskeletal computer simulation model.Journal of orthopaedicsArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
The effects of tears of the anterior cruciate ligament on knee kinematics and contact mechanics during dynamic everyday activities, such as gait, remains unclear. The objective of this study was to characterize anterior cruciate ligament-deficient knee contact mechanics and kinematics during simulated gait. Nine human cadaveric knees were each augmented with a sensor capable of measuring dynamic normal contact stresses on the tibial plateau, mounted on a load-controlled simulator, and subjected to physiological, multidirectional, dynamic loads to mimic gait. Using a mixed model with random knee identifiers, confidence intervals were constructed for contact stress before and after anterior cruciate ligament transection at two points in the gait cycle at which axial force peaked (14% and 45% of the gait cycle). Kinematic and contact mechanics changes after anterior cruciate ligament transection were highly variable across knees. Nonetheless, a statistically significant increase in contact stress in the posterior-central aspect of the medial tibial plateau at 45% of the gait cycle was identified, the location of which corresponds to the location of degenerative changes that are frequently found in patients with chronic anterior cruciate ligament injury. The variability in the contact stress in other regions of the medial plateau at 45% of the gait cycle was partly explained by the variations in osseous geometry across the nine knees tested. At 14% of gait, there was no significant change in peak contact stress after anterior cruciate ligament transection in any of the four quadrants, and none of the possible explanatory variables showed statistical significance. Understanding the variable effect of anterior cruciate ligament injury on contact mechanics based on geometric differences in osseous anatomy is of paramount clinical importance and may be invaluable to select the best reconstruction techniques and counsel patients on their individual risk of subsequent chondral degeneration.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.